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NCT00714571 · ClinicalTrials.gov registry record · Phase 1
Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)
A Phase 1 study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- Phase 1
- Development phase
- 82
- Enrollment target
NCT00714571: Completed Phase 1 study, sponsored by VA Office of Research and Development.
NCT00714571 is a Phase 1 study that has completed, run by VA Office of Research and Development. The registered enrollment target is 82 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00714571, a Phase 1 study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 82 participants
- Enrollment target
Study Summary
Memory deficits are common after traumatic brain injuries (TBI) and are characteristic of various forms of dementia, such as Alzheimer's disease and its common precursor mild cognitive impairment (MCI). This project intends to assess the efficacy of cognitive rehabilitation in these patient populations. We will also use neuroimaging (functional magnetic resonance imaging - fMRI) to assess changes in brain activity that occur following cognitive rehabilitation.
Primary Outcome
Accuracy (Percent correct) for trained stimuli. Stage 1: Object location association test Stage 2: Face name association test
Interventions
- BEHAVIORAL Mnemonic strategy training (MST)
- BEHAVIORAL Repeated exposure (XP)
- BEHAVIORAL Subtracting Cues training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2008-07 |
| Est. Completion | 2014-09 |
| Phase | Phase 1 |
What the finished NCT00714571 record still lists
NCT00714571 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% higher).
The record links to 0 conditions, and to 3 interventions - of which Mnemonic strategy training (MST) is the first listed.
NCT00714571 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00714571 about?
NCT00714571 is a clinical study titled "Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)". Memory deficits are common after traumatic brain injuries (TBI) and are characteristic of various forms of dementia, such as Alzheimer's disease and its common precursor mild cognitive impairment (MCI). This project intends to assess the efficacy of cognitive rehabilitation in these patient populati...
What is the current status of trial NCT00714571?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 82 participants. The study started on 2008-07. Estimated completion is 2014-09.
What interventions are being tested in trial NCT00714571?
The interventions under investigation include: Mnemonic strategy training (MST) (BEHAVIORAL), Repeated exposure (XP) (BEHAVIORAL), Subtracting Cues training (BEHAVIORAL).
Who is sponsoring clinical trial NCT00714571?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00714571's enrollment target sits among peer trials
82 669th of 2000 higher than 1,330 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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