VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 31 of 34

COMPLETED Phase 1

Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity

NCT00953849

COMPLETED NA

Telephone Care Coordination for Smokers in VA Mental Health Clinics

NCT00724308

COMPLETED Phase 4

Telemedicine Outreach for Post Traumatic Stress in CBOCs

NCT00821678

COMPLETED NA

Cognitive Behavior Therapy and Work Outcome

NCT00810355

COMPLETED NA

Telehealth-Based Exercise Program to Treat Fatigue in MS

NCT01198977

COMPLETED NA

Engaging Homeless Veterans in Primary Care

NCT00858507

COMPLETED NA

Care Partners: Web-based Support for Caregivers of Veterans Undergoing Chemotherapy

NCT00983892

COMPLETED Phase 1

Phase 1 Trial of Type II Collagen (CII) APL A12 in Rheumatoid Arthritis Patients

NCT01123655

COMPLETED NA

Controlling Hypertension Outcomes by Improved Communication & Engagement

NCT01134887

COMPLETED Early Phase 1

Respiratory and Autonomic Plasticity Following Intermittent Hypoxia

NCT00860743

COMPLETED NA

Training in Goal-directed Attention Regulation for Individuals With Brain Injury

NCT01035606

COMPLETED Phase 2

Pioglitazone for Lung Cancer Chemoprevention

NCT00780234

COMPLETED NA

Exercise as an Adjuvant to Aphasia Therapy

NCT01113879

COMPLETED Phase 2

Improving Obstructive Sleep Apnea Management Via Wireless Telemonitoring

NCT00682838

COMPLETED Phase 4

CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial

NCT00847912

COMPLETED NA

A Comparison of Cognitive Processing Therapy (CPT) Versus Present Centered Therapy (PCT) for Veterans

NCT00607815

COMPLETED NA

Evaluating Vocational Materials for Incarcerated Veterans With Mental Illness or Substance Abuse

NCT00648115

COMPLETED NA

Neural Prostheses and Gait Performance: Model-Based Strategies

NCT00991406

COMPLETED Phase 3

A Randomized Controlled Trial of Mandatory Naps for Physicians in Training

NCT00874510

COMPLETED NA

Multimodal Treatment of Phonological Alexia: Behavioral & fMRI Outcomes

NCT00827268

COMPLETED NA

Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans

NCT00805532

COMPLETED

Quantitative Automated Lesion Detection of Traumatic Brain Injury

NCT01022307

COMPLETED

Patient-Centered Heart Failure Trial

NCT00461513

COMPLETED NA

Enhancing Equitable and Effective (E-3) Post Traumatic Stress Disorder (PTSD) Disability Assessment

NCT00699660

COMPLETED NA

Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans

NCT00691626

COMPLETED NA

Strength Training for Skeletal Muscle Adaptation After Stroke

NCT00827827

COMPLETED NA

Cognitive-Behavioral Therapy in Veterans With Schizophrenia

NCT00688259

COMPLETED

Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI) (CASL)

NCT00880555

COMPLETED Phase 2

Expiratory Muscle Training for Persons With Neurodegenerative Disease

NCT00856518

COMPLETED NA

Doppler Ultrasound Probe for Blood Flow Detection in Severe Upper Gastrointestinal Hemorrhage

NCT00732212

COMPLETED NA

Veterans Telemedicine Outreach for PTSD Services

NCT00645047

COMPLETED

Learning and Relationships in Primary Care

NCT00657696

COMPLETED

Formative Evaluation in Implementation Research: Guideline Development

NCT00683540

COMPLETED Phase 4

Veteran Stress and Learning Study

NCT00674570

COMPLETED NA

Bright Light: An Adjunct Treatment for Combat Posttraumatic Stress Disorder (PTSD)

NCT00701064

COMPLETED NA

Supplementing Hearing Aids With Computerized Auditory Training

NCT00727337

COMPLETED Phase 1

Adaptive Physical Activity for Chronic Stroke

NCT00773370

COMPLETED NA

Adapting Tools to Implement Stroke Risk Management to Veterans

NCT00355147

COMPLETED NA

Effect of Weight Loss on Prostate Cancer Pathology

NCT00475982

COMPLETED Phase 2

Topiramate to Aid Smoking Cessation in Alcohol Dependent Men

NCT00802412

COMPLETED Phase 2

Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease

NCT00984308

COMPLETED

Women's Post Traumatic Stress Disorder (PTSD) Research Study

NCT01304940

COMPLETED Phase 2

Benefits Counseling to Preserve Function Among Disability Applicants

NCT00715650

COMPLETED NA

Implementation of Real-time ADE Surveillance and Decision Support

NCT00780572

COMPLETED NA

Outlook Quality of Life Intervention

NCT00784095

COMPLETED NA

Cognitive Behavior Therapy (CBT) and Mirror Training for Phantom Limb Pain

NCT00731614

COMPLETED NA

Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep

NCT00732199

TERMINATED Phase 3

Buspirone as a Potential Treatment for Recurrent Central Apnea

NCT00746954

COMPLETED NA

Testing the Helpfulness of 2 Decision Aids for Prostate Cancer

NCT00432601

COMPLETED

Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke

NCT00721357

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.