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NCT00708799 · ClinicalTrials.gov registry record · Phase 2
Efficacy of Macrolide Immunomodulation in Severe Sepsis.
A Phase 2 study, sponsored by VA Office of Research and Development.
- Terminated
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT00708799: Clinical Trial Phase 2 study, sponsored by VA Office of Research and Development.
NCT00708799 is a Phase 2 study that was terminated before completion, run by VA Office of Research and Development. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00708799, a Phase 2 study, was terminated before completion, sponsored by VA Office of Research and Development.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether macrolide treatment of patients with severe sepsis has an advantageous immunomodulatory and clinical effect compared to severe septic patients without macrolide therapy. Our main hypothesis is macrolide use in addition to standard therapy in severe septic patients has an advantageous immunomodulatory and clinical effect compared to patients with severe sepsis not treated with a macrolide.
Interventions
- OTHER Azithromycin on admission - not enrolled in the RCT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2007-11 |
| Est. Completion | 2013-11 |
| Phase | Phase 2 |
Why NCT00708799 stopped before completion
NCT00708799 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 1 intervention - of which Azithromycin on admission - not enrolled in the RCT is the first listed.
NCT00708799 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00708799 about?
NCT00708799 is a clinical study titled "Efficacy of Macrolide Immunomodulation in Severe Sepsis.". The purpose of this study is to determine whether macrolide treatment of patients with severe sepsis has an advantageous immunomodulatory and clinical effect compared to severe septic patients without macrolide therapy. Our main hypothesis is macrolide use in addition to standard therapy in severe s...
What is the current status of trial NCT00708799?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2007-11. Estimated completion is 2013-11.
What interventions are being tested in trial NCT00708799?
The interventions under investigation include: Azithromycin on admission - not enrolled in the RCT (OTHER).
Who is sponsoring clinical trial NCT00708799?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00708799's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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