Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05831774 · ClinicalTrials.gov registry record · Phase 4
IO Vancomycin in TSA
A Phase 4 study of Shoulder Injuries, sponsored by The Methodist Hospital Research Institute.
- Active
- Registry status
- Phase 4
- Development phase
- 33
- Enrollment target
- 1
- Study location
NCT05831774: Active Phase 4 study of Shoulder Injuries, sponsored by The Methodist Hospital Research Institute.
NCT05831774 is a Phase 4 study of Shoulder Injuries that is active but no longer recruiting, run by The Methodist Hospital Research Institute. The registered enrollment target is 33 participants, below the 261-participant average among 10 other Shoulder Injuries trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05831774, a Phase 4 study of Shoulder Injuries, is active but no longer recruiting, sponsored by The Methodist Hospital Research Institute.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 33 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to compare two different antibiotic regimens and techniques during total shoulder arthroplasty. Primary Objective: Comparable levels of vancomycin will be found in bone, soft tissue, and systemic samples between patient groups. Secondary Objective: Compare 30 day and 90 day post-operative complication rates (infection) between the control (standard IV administration of vancomycin) vs the interventional group (intraosseous administration of vancomycin). The investigators hypothesize that there will be no difference in complication (infection) rates between groups.
Primary Outcome
Comparable levels of vancomycin will be found in systemic samples between patient groups.
Conditions Studied
Interventions
- DRUG Intervention - Intraosseous (IO) administration of vancomycin
- DRUG Control - Standard IV administration of vancomycin
Study Locations (1)
Texas
- Houston Methodist Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2023-06-01 |
| Est. Completion | 2026-03-10 |
| Phase | Phase 4 |
What the registry record for NCT05831774 still lists
NCT05831774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 261-participant average among 10 other Shoulder Injuries trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Shoulder Injuries appearing as the primary indexed condition, and to 2 interventions - of which Intervention - Intraosseous (IO) administration of vancomycin is the first listed.
NCT05831774 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05831774 about?
NCT05831774 is a clinical study titled "IO Vancomycin in TSA". The purpose of this study is to compare two different antibiotic regimens and techniques during total shoulder arthroplasty. Primary Objective: Comparable levels of vancomycin will be found in bone, soft tissue, and systemic samples between patient groups. Secondary Objective: Compare 30 day and 9...
What is the current status of trial NCT05831774?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 33 participants. The study started on 2023-06-01. Estimated completion is 2026-03-10.
What conditions does trial NCT05831774 study?
This clinical trial studies the following conditions: Shoulder Injuries.
What interventions are being tested in trial NCT05831774?
The interventions under investigation include: Intervention - Intraosseous (IO) administration of vancomycin (DRUG), Control - Standard IV administration of vancomycin (DRUG).
Who is sponsoring clinical trial NCT05831774?
This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05831774 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Shoulder Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05831774's enrollment target sits among peer trials
33 9th of 10 higher than 2 of 10 other Shoulder Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Shoulder Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Subscap Reverse Shoulder Arthroplasty
RECRUITING · NA
-
MDR - Comprehensive Primary Revision Stems PMCF
RECRUITING
-
Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
RECRUITING
-
Subscapularis Repair Augmentation for Total Shoulder Arthroplasty
RECRUITING · NA
-
Zimmer Biomet Shoulder Arthroplasty PMCF
RECRUITING · NA
-
Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02861898 · 33 participants · Phase 1
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
- NCT04871607 · 33 participants · Phase 2
Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma
- NCT05071937 · 33 participants · Phase 2
ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
- NCT05168618 · 33 participants · Phase 2
Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI