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NCT06798623 · ClinicalTrials.gov registry record · Phase 1

Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells

A Phase 1 study of Anterior Cruciate Ligament Reconstruction, sponsored by The Methodist Hospital Research Institute.

Recruiting
Registry status
Phase 1
Development phase
15
Enrollment target
1
Study location

NCT06798623 is a Phase 1 study of Anterior Cruciate Ligament Reconstruction that is actively recruiting participants, run by The Methodist Hospital Research Institute. The registered enrollment target is 15 participants, below the 293-participant average among 11 other Anterior Cruciate Ligament Reconstruction trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06798623, a Phase 1 study of Anterior Cruciate Ligament Reconstruction, is actively recruiting participants, sponsored by The Methodist Hospital Research Institute.

RECRUITING
Registry status
Phase 1
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This study is designed as a prospective, open label, single arm pilot clinical study that will establish the safety and efficacy of a single injection of mesenchymal stromal cells in patients. Each subject will receive one intra-articular injection of autologous mesenchymal stromal cells derived from infrapatellar fat pad (FP-MSC) tissue samples collected from the subject during anterior cruciate ligament (ACL) reconstruction surgery.

Interventions

  • BIOLOGICAL Autologous Mesenchymal Stromal Cells

Study Locations (1)

Texas

  • Houston Methodist Hospital - Houston

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2026-04
Est. Completion 2030-03
Phase Phase 1

What the Registry Record Tells You About NCT06798623

The ClinicalTrials.gov registry entry for NCT06798623 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 293-participant average among 11 other Anterior Cruciate Ligament Reconstruction trials with a reported enrollment target (95% lower). The listed sponsor is The Methodist Hospital Research Institute, which has 126 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Anterior Cruciate Ligament Reconstruction appearing as the primary indexed condition, and to 1 intervention - of which Autologous Mesenchymal Stromal Cells is the first listed.

NCT06798623 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06798623 about?

NCT06798623 is a clinical study titled "Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells". This study is designed as a prospective, open label, single arm pilot clinical study that will establish the safety and efficacy of a single injection of mesenchymal stromal cells in patients. Each subject will receive one intra-articular injection of autologous mesenchymal stromal cells derived fro...

What is the current status of trial NCT06798623?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2026-04. Estimated completion is 2030-03.

What conditions does trial NCT06798623 study?

This clinical trial studies the following conditions: Anterior Cruciate Ligament Reconstruction.

What interventions are being tested in trial NCT06798623?

The interventions under investigation include: Autologous Mesenchymal Stromal Cells (BIOLOGICAL).

Who is sponsoring clinical trial NCT06798623?

This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06798623 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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