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NCT06798623 · ClinicalTrials.gov registry record · Phase 1
Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells
A Phase 1 study of Anterior Cruciate Ligament Reconstruction, sponsored by The Methodist Hospital Research Institute.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT06798623: Recruiting Phase 1 study of Anterior Cruciate Ligament Reconstruction, sponsored by The Methodist Hospital Research Institute.
NCT06798623 is a Phase 1 study of Anterior Cruciate Ligament Reconstruction that is actively recruiting participants, run by The Methodist Hospital Research Institute. The registered enrollment target is 15 participants, below the 293-participant average among 11 other Anterior Cruciate Ligament Reconstruction trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06798623, a Phase 1 study of Anterior Cruciate Ligament Reconstruction, is actively recruiting participants, sponsored by The Methodist Hospital Research Institute.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed as a prospective, open label, single arm pilot clinical study that will establish the safety and efficacy of a single injection of mesenchymal stromal cells in patients. Each subject will receive one intra-articular injection of autologous mesenchymal stromal cells derived from infrapatellar fat pad (FP-MSC) tissue samples collected from the subject during anterior cruciate ligament (ACL) reconstruction surgery.
Primary Outcome
Participants will be asked via a follow-up phone call following injection whether or not they have experienced any adverse events following the injection. They will be assessed at all remaining standard of care follow up visits and staff will inquire about adverse events.
Conditions Studied
Interventions
- BIOLOGICAL Autologous Mesenchymal Stromal Cells
Study Locations (1)
Texas
- Houston Methodist Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2026-04 |
| Est. Completion | 2030-03 |
| Phase | Phase 1 |
What NCT06798623 shows while recruiting
NCT06798623 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 293-participant average among 11 other Anterior Cruciate Ligament Reconstruction trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Anterior Cruciate Ligament Reconstruction appearing as the primary indexed condition, and to 1 intervention - of which Autologous Mesenchymal Stromal Cells is the first listed.
NCT06798623 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06798623 about?
NCT06798623 is a clinical study titled "Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells". This study is designed as a prospective, open label, single arm pilot clinical study that will establish the safety and efficacy of a single injection of mesenchymal stromal cells in patients. Each subject will receive one intra-articular injection of autologous mesenchymal stromal cells derived fro...
What is the current status of trial NCT06798623?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2026-04. Estimated completion is 2030-03.
What conditions does trial NCT06798623 study?
This clinical trial studies the following conditions: Anterior Cruciate Ligament Reconstruction.
What interventions are being tested in trial NCT06798623?
The interventions under investigation include: Autologous Mesenchymal Stromal Cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT06798623?
This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06798623 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06798623's enrollment target sits among peer trials
15 12th of 11 the lowest of 11 other Anterior Cruciate Ligament Reconstruction trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anterior Cruciate Ligament Reconstruction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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