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ClinicalTrials.gov 8 recruiting now official registry

Urothelial Carcinoma Bladder clinical trials

8 of 17 indexed Urothelial Carcinoma Bladder trials are currently recruiting.

17 US clinical trials · 8 currently recruiting

Urothelial Carcinoma Bladder is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, running 3 of these trials.

The research picture

Urothelial Carcinoma Bladder has 17 registered US clinical trials, 8 of them open to new participants right now, about 47% of the total.

8
recruiting participants now
47%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
3
top sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 16Phase 26Phase 33

Active & Recent Trials

17 total, page 1 of 1

RECRUITING 416 participants

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

Elephas

NCT05520099

RECRUITING Phase 1 150 participants

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

Aktis Oncology

NCT07020117

RECRUITING Phase 2 147 participants

Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy

University of Florida

NCT06184516

RECRUITING Phase 2 63 participants

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05312671

RECRUITING Phase 1 55 participants

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

Aura Biosciences

NCT05483868

RECRUITING Phase 1 32 participants

Targeting Androgen Signaling in Urothelial Cell Carcinoma - Neoadjuvant

Brown University

NCT05839119

RECRUITING Phase 2 20 participants

Renal Retention in High Grade Upper Tract Urothelial Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05656235

RECRUITING Phase 1 10 participants

Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer

Abramson Cancer Center at Penn Medicine

NCT06586255

ACTIVE NOT RECRUITING Phase 3 240 participants

A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer

UroGen Pharma

NCT05243550

ACTIVE NOT RECRUITING Phase 3 99 participants

A Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder Cancer

UroGen Pharma

NCT06331299

ACTIVE NOT RECRUITING 80 participants

Evaluating Bladder CARE™, a New Non-Invasive Urine Test, for Bladder Cancer Detection in Inconclusive Cases

Pangea Laboratory

NCT06870253

ACTIVE NOT RECRUITING Phase 2 63 participants

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

IO Biotech

NCT05077709

ACTIVE NOT RECRUITING Phase 2 33 participants

Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer

The Methodist Hospital Research Institute

NCT05241340

ACTIVE NOT RECRUITING Phase 2 27 participants

Intravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04386746

ACTIVE NOT RECRUITING Phase 1 12 participants

Phase Ib of L-NMMA and Pembrolizumab

The Methodist Hospital Research Institute

NCT03236935

COMPLETED Phase 1 78 participants

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Ikena Oncology

NCT04200963

COMPLETED Phase 3 8 participants

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

UroGen Pharma

NCT05136898

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Urothelial Carcinoma Bladder Trial Landscape

17 indexed Urothelial Carcinoma Bladder studies · 8 recruiting (47%).

Phase mix: 3 late (III/IV) vs 12 early (I/II).

Top sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Urothelial Carcinoma Bladder?

PlainTrial tracks 17 US clinical trials for Urothelial Carcinoma Bladder, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Urothelial Carcinoma Bladder?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.