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ClinicalTrials.gov 8 recruiting now early-phase tilt small index

Urothelial Carcinoma Bladder: early-phase trial registry

8 of 17 indexed Urothelial Carcinoma Bladder trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 8 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Urothelial Carcinoma Bladder: 17 US clinical trials tracked, 8 recruiting.

Urothelial Carcinoma Bladder is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, running 3 of these trials.

Enrollment posture brief

Registry condition urothelial-carcinoma-bladder

OPEN 8 | RECR 47% | LATE 3 | EARLY 12 | RANK #1004 | SPON 3

Nearest open-share peer: Bone Loss (47% recruiting · 17 trials)

Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Urothelial Carcinoma Bla (th…47%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Urothelial Carcinoma Bladder

Urothelial Carcinoma Bladder lists 8 open slots (47% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Urothelial Carcinoma Bladder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Urothelial Carcinoma Bladder recruits in line with its size-band peers.

    8 of 17 indexed trials (47.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Urothelial Carcinoma Bladder research.

    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins accounts for 3 of 17 trials (17.6%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most Urothelial Carcinoma Bladder trials plan to enrol fewer than 100 people.

    Median target enrolment is 63 among the 17 trials that report a genuine target (sentinel values excluded). 13 of those (76.5%) plan for fewer than 100 participants.

  4. Urothelial Carcinoma Bladder research is mostly interventional.

    15 interventional and 2 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 26Phase 33

Open and recent trials

17 total, page 1 of 1

RECRUITING 416 participants

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

Elephas

NCT05520099

RECRUITING Phase 1 150 participants

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

Aktis Oncology

NCT07020117

RECRUITING Phase 2 147 participants

Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy

University of Florida

NCT06184516

RECRUITING Phase 2 63 participants

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05312671

RECRUITING Phase 1 55 participants

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

Aura Biosciences

NCT05483868

RECRUITING Phase 1 32 participants

Targeting Androgen Signaling in Urothelial Cell Carcinoma - Neoadjuvant

Brown University

NCT05839119

RECRUITING Phase 2 20 participants

Renal Retention in High Grade Upper Tract Urothelial Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05656235

RECRUITING Phase 1 10 participants

Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer

Abramson Cancer Center at Penn Medicine

NCT06586255

ACTIVE NOT RECRUITING Phase 3 240 participants

A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer

UroGen Pharma

NCT05243550

ACTIVE NOT RECRUITING Phase 3 99 participants

A Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder Cancer

UroGen Pharma

NCT06331299

ACTIVE NOT RECRUITING 80 participants

Evaluating Bladder CARE™, a New Non-Invasive Urine Test, for Bladder Cancer Detection in Inconclusive Cases

Pangea Laboratory

NCT06870253

ACTIVE NOT RECRUITING Phase 2 63 participants

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

IO Biotech

NCT05077709

ACTIVE NOT RECRUITING Phase 2 33 participants

Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer

The Methodist Hospital Research Institute

NCT05241340

ACTIVE NOT RECRUITING Phase 2 27 participants

Intravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04386746

ACTIVE NOT RECRUITING Phase 1 12 participants

Phase Ib of L-NMMA and Pembrolizumab

The Methodist Hospital Research Institute

NCT03236935

COMPLETED Phase 1 78 participants

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Ikena Oncology

NCT04200963

COMPLETED Phase 3 8 participants

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

UroGen Pharma

NCT05136898

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6
Phase 3 3

Named interventions

Most-linked intervention names on Urothelial Carcinoma Bladder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

UGN-102 Drug
2 trials
Pembrolizumab Drug
2 trials
IK-175 and nivolumab Drug
1 trials
IK-175 Drug
1 trials
UGN-103 Drug
1 trials
Radical Cystectomy + pelvic lymph node dissection + urinary diversion Procedure
1 trials
IO102-IO103 in combination with pembrolizumab Drug
1 trials
Reproductive organ sparing radical cystectomy Procedure
1 trials

US sites by state

Facility locations filed on Urothelial Carcinoma Bladder trials. A trial with sites in several states counts in each.

Texas 7 trials
New York 7 trials
Maryland 7 trials
California 6 trials
Tennessee 5 trials
Florida 5 trials
Pennsylvania 4 trials
Washington 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Urothelial Carcinoma Bladder page

17 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Urothelial Carcinoma Bladder condition card totals 17 registered trials; most-linked intervention UGN-102; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.