The Methodist Hospital Research Institute
The Methodist Hospital Research Institute sponsors 126 registered US clinical trials on ClinicalTrials.gov, 49 of them currently recruiting, and 48 completed. 12 of these trials are in Phase 3-4 (later-stage) and 65 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Urge Incontinence, with 2 trials.
Trial Pipeline
126 total, page 2 of 3
Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer
NCT05241340
Study in ALS With Abatacept & IL-2
NCT06307301
Neoadjuvant Atezolizumab in Cutaneous Melanoma
NCT04020809
Durvalumab with Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer
NCT03820141
ORIF Distal Radius Blood Flow Restriction Therapy
NCT06136286
T-regulatory Cells in ALS
NCT04055623
Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer
NCT03742245
Phase Ib of L-NMMA and Pembrolizumab
NCT03236935
Mesenchymal Stromal Cells in Living Donor Kidney Transplantation
NCT03478215
IO Vancomycin Spine
NCT06748144
Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker
NCT07060001
NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal Cancers
NCT07060014
Knee Isometric Program (KIP) Home Exercise Programs (HEP) Physical Therapy (PT) Study
NCT06536426
Low-intensity Shockwave Therapy for Post-radical Prostatectomy Erectile Dysfunction
NCT06219785
Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients
NCT06232317
Optimization of OnabotulinumtoxinA (BTX-A) Injection for the Treatment of Neurogenic Lower Urinary Tract Dysfunction
NCT06059066
Survey of Human Rabies Immune Globulin Safety in Children
NCT05382650
Ultrasound Evaluation for Baxter VASCU-GUARD Vascular Patches Post-Endarterectomy and Complications Assessment
NCT07048067
Neuromuscular Training in Female Youth Soccer
NCT06136299
Usability, Acceptability, and Safety of Virtual Reality-based Cognitive Intervention
NCT05583903
Procedural Discomfort Related to Number of Intradetrusor Botox Injections
NCT05652036
Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy
NCT04911166
Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study
NCT06725485
Opioid Use After Thyroid and Parathyroid Surgeries
NCT04955444
Docetaxel Chemotherapy and Pembrolizumab Plus Interleukin-12 Gene Therapy in Triple Negative Breast Cancer
NCT04095689
Mapping of the Human Brainstem During Continence and Micturition: Noninvasive 7-T fMRI Study
NCT04846387
68 Ga-PSMA for High Risk Prostate Cancer
NCT04614363
Educating Women About Pelvic Floor Disorders During Pregnancy
NCT05440539
Sleep & Stress in Healthcare Providers After Defined Music Intervention Measure by 7-Tesla fMRI & Actigraphy
NCT05980429
Intraosseous Morphine in Primary TKA
NCT04388111
Convalescent Plasma for the Treatment of COVID-19 (Coronavirus Disease 2019)
NCT04554992
Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol
NCT04042233
Improving Adherence to Rabies PEP Guideline Recommendations
NCT04213950
Motion Capture: Baseball Swing
NCT04503070
7T MRI to Evaluate Cartilage Defects in the Knee
NCT04118023
Trial to Study Electro-Acupuncture in Subjects With Chemotherapy-Induced Peripheral Neuropathy
NCT07455409
Low Dose IL2 Immunotherapy in AD
NCT05821153
Brain Imaging in Men With Lower Urinary Tract Symptoms
NCT03991429
Explore Transplant @Home Within Kaiser Permanente Southern California
NCT03389932
Brain Targets in Patients With Bladder Emptying Difficulties
NCT03574610
Heart Failure Hospital Readmissions and Physical Therapy
NCT03517514
Blood Flow Restriction Training for The Shoulder
NCT04540367
SBRT and Oncolytic Virus Therapy Before Pembrolizumab for Metastatic TNBC and NSCLC
NCT03004183
TAK-228 Plus Tamoxifen in Patients With ER-Positive, HER2-negative Breast Cancer
NCT02988986
Deep Brain Stimulation in Patients With LUTS
NCT03202251
L-NMMA Plus Taxane Chemotherapy in Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients
NCT02834403
Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis
NCT03241784
Explore Transplant at Home: Improving Low-Income ESRD Patients' Transplant Knowledge
NCT02268682
Your Path to Transplant: A Randomized Control Trial of A Tailored Computer Education Intervention for Living Donor Kidney Transplant
NCT02181114
Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma
NCT02176720
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 30 |
| Phase 2 | 35 |
| Phase 3 | 2 |
| Phase 4 | 10 |
What the Pipeline for The Methodist Hospital Research Institute Shows
According to the ClinicalTrials.gov registry, The Methodist Hospital Research Institute is linked to 126 US clinical trials across every stage of research activity. Of those, 49 studies are currently recruiting, about 39% of the sponsor's indexed portfolio, and 48 are already marked complete, representing roughly 38% of the total.
The phase mix for The Methodist Hospital Research Institute reports 12 late-stage studies (Phase 3 and Phase 4 combined) and 65 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Methodist Hospital Research Institute is Urge Incontinence with 2 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.