The Methodist Hospital Research Institute

126 total trials 49 currently recruiting 48 completed

The Methodist Hospital Research Institute sponsors 126 registered US clinical trials on ClinicalTrials.gov, 49 of them currently recruiting, and 48 completed. 12 of these trials are in Phase 3-4 (later-stage) and 65 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Urge Incontinence, with 2 trials.

Trial Pipeline

126 total, page 2 of 3

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer

NCT05241340

ACTIVE NOT RECRUITING Phase 1

Study in ALS With Abatacept & IL-2

NCT06307301

ACTIVE NOT RECRUITING Phase 1

Neoadjuvant Atezolizumab in Cutaneous Melanoma

NCT04020809

ACTIVE NOT RECRUITING Phase 2

Durvalumab with Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer

NCT03820141

ACTIVE NOT RECRUITING NA

ORIF Distal Radius Blood Flow Restriction Therapy

NCT06136286

ACTIVE NOT RECRUITING Phase 2

T-regulatory Cells in ALS

NCT04055623

ACTIVE NOT RECRUITING Phase 1

Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer

NCT03742245

ACTIVE NOT RECRUITING Phase 1

Phase Ib of L-NMMA and Pembrolizumab

NCT03236935

ACTIVE NOT RECRUITING Phase 2

Mesenchymal Stromal Cells in Living Donor Kidney Transplantation

NCT03478215

NOT YET RECRUITING Phase 2

IO Vancomycin Spine

NCT06748144

NOT YET RECRUITING Phase 2

Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker

NCT07060001

NOT YET RECRUITING Phase 1

NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal Cancers

NCT07060014

TERMINATED NA

Knee Isometric Program (KIP) Home Exercise Programs (HEP) Physical Therapy (PT) Study

NCT06536426

TERMINATED NA

Low-intensity Shockwave Therapy for Post-radical Prostatectomy Erectile Dysfunction

NCT06219785

COMPLETED NA

Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients

NCT06232317

COMPLETED NA

Optimization of OnabotulinumtoxinA (BTX-A) Injection for the Treatment of Neurogenic Lower Urinary Tract Dysfunction

NCT06059066

TERMINATED

Survey of Human Rabies Immune Globulin Safety in Children

NCT05382650

COMPLETED

Ultrasound Evaluation for Baxter VASCU-GUARD Vascular Patches Post-Endarterectomy and Complications Assessment

NCT07048067

COMPLETED NA

Neuromuscular Training in Female Youth Soccer

NCT06136299

COMPLETED NA

Usability, Acceptability, and Safety of Virtual Reality-based Cognitive Intervention

NCT05583903

COMPLETED Phase 4

Procedural Discomfort Related to Number of Intradetrusor Botox Injections

NCT05652036

TERMINATED Phase 1

Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy

NCT04911166

COMPLETED Phase 4

Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study

NCT06725485

COMPLETED NA

Opioid Use After Thyroid and Parathyroid Surgeries

NCT04955444

TERMINATED Phase 2

Docetaxel Chemotherapy and Pembrolizumab Plus Interleukin-12 Gene Therapy in Triple Negative Breast Cancer

NCT04095689

COMPLETED

Mapping of the Human Brainstem During Continence and Micturition: Noninvasive 7-T fMRI Study

NCT04846387

COMPLETED Phase 1

68 Ga-PSMA for High Risk Prostate Cancer

NCT04614363

COMPLETED NA

Educating Women About Pelvic Floor Disorders During Pregnancy

NCT05440539

COMPLETED NA

Sleep & Stress in Healthcare Providers After Defined Music Intervention Measure by 7-Tesla fMRI & Actigraphy

NCT05980429

COMPLETED Phase 4

Intraosseous Morphine in Primary TKA

NCT04388111

COMPLETED Phase 1

Convalescent Plasma for the Treatment of COVID-19 (Coronavirus Disease 2019)

NCT04554992

COMPLETED Phase 4

Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol

NCT04042233

COMPLETED NA

Improving Adherence to Rabies PEP Guideline Recommendations

NCT04213950

COMPLETED

Motion Capture: Baseball Swing

NCT04503070

COMPLETED

7T MRI to Evaluate Cartilage Defects in the Knee

NCT04118023

COMPLETED NA

Trial to Study Electro-Acupuncture in Subjects With Chemotherapy-Induced Peripheral Neuropathy

NCT07455409

COMPLETED Phase 1

Low Dose IL2 Immunotherapy in AD

NCT05821153

COMPLETED

Brain Imaging in Men With Lower Urinary Tract Symptoms

NCT03991429

COMPLETED NA

Explore Transplant @Home Within Kaiser Permanente Southern California

NCT03389932

COMPLETED NA

Brain Targets in Patients With Bladder Emptying Difficulties

NCT03574610

COMPLETED

Heart Failure Hospital Readmissions and Physical Therapy

NCT03517514

COMPLETED NA

Blood Flow Restriction Training for The Shoulder

NCT04540367

COMPLETED Phase 2

SBRT and Oncolytic Virus Therapy Before Pembrolizumab for Metastatic TNBC and NSCLC

NCT03004183

COMPLETED Phase 2

TAK-228 Plus Tamoxifen in Patients With ER-Positive, HER2-negative Breast Cancer

NCT02988986

COMPLETED

Deep Brain Stimulation in Patients With LUTS

NCT03202251

COMPLETED Phase 1

L-NMMA Plus Taxane Chemotherapy in Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients

NCT02834403

COMPLETED Phase 1

Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis

NCT03241784

COMPLETED NA

Explore Transplant at Home: Improving Low-Income ESRD Patients' Transplant Knowledge

NCT02268682

COMPLETED NA

Your Path to Transplant: A Randomized Control Trial of A Tailored Computer Education Intervention for Living Donor Kidney Transplant

NCT02181114

TERMINATED Phase 1

Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma

NCT02176720

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What the Pipeline for The Methodist Hospital Research Institute Shows

According to the ClinicalTrials.gov registry, The Methodist Hospital Research Institute is linked to 126 US clinical trials across every stage of research activity. Of those, 49 studies are currently recruiting, about 39% of the sponsor's indexed portfolio, and 48 are already marked complete, representing roughly 38% of the total.

The phase mix for The Methodist Hospital Research Institute reports 12 late-stage studies (Phase 3 and Phase 4 combined) and 65 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for The Methodist Hospital Research Institute is Urge Incontinence with 2 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.