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NCT04390425 · ClinicalTrials.gov registry record · NA
Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery
A NA study of Limb Occlusion Pressure, sponsored by The Methodist Hospital Research Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 400
- Enrollment target
- 1
- Study location
NCT04390425: Recruiting NA study of Limb Occlusion Pressure, sponsored by The Methodist Hospital Research Institute.
NCT04390425 is a NA study of Limb Occlusion Pressure that is actively recruiting participants, run by The Methodist Hospital Research Institute. The registered enrollment target is 400 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04390425, a NA study of Limb Occlusion Pressure, is actively recruiting participants, sponsored by The Methodist Hospital Research Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Currently a standard tourniquet pressure is used for orthopedic surgeries. High tourniquet pressure had been associated with adverse side effects such as ischemia, muscle weakness, and post operative pain. Limb Occlusion Pressure, LOP, is based off the patient's systolic blood pressure plus a safety margin and is typically much lower than standard tourniquet pressure. The aim of this study is to determine if using LOP during orthopedic surgeries decreases post-operative pain and opioid consumption and improves patient's outcomes.
Primary Outcome
Visual analog scale from 0 (no pain) to 10 (worst pain imaginable)
Conditions Studied
Interventions
- DEVICE Experimental - Limb Occlusion pressure
Study Locations (1)
Texas
- Houston Methodist Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2018-04-06 |
| Est. Completion | 2026-12 |
| Phase | NA |
What NCT04390425 shows while recruiting
NCT04390425 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Limb Occlusion Pressure appearing as the primary indexed condition, and to 1 intervention - of which Experimental - Limb Occlusion pressure is the first listed.
NCT04390425 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04390425 about?
NCT04390425 is a clinical study titled "Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery". Currently a standard tourniquet pressure is used for orthopedic surgeries. High tourniquet pressure had been associated with adverse side effects such as ischemia, muscle weakness, and post operative pain. Limb Occlusion Pressure, LOP, is based off the patient's systolic blood pressure plus a safety...
What is the current status of trial NCT04390425?
This trial is currently recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2018-04-06. Estimated completion is 2026-12.
What conditions does trial NCT04390425 study?
This clinical trial studies the following conditions: Limb Occlusion Pressure.
What interventions are being tested in trial NCT04390425?
The interventions under investigation include: Experimental - Limb Occlusion pressure (DEVICE).
Who is sponsoring clinical trial NCT04390425?
This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04390425 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04390425's enrollment target sits among peer trials
400 246th of 2000 higher than 1,734 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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