The Cleveland Clinic

688 total trials 99 currently recruiting 437 completed

The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.

Trial Pipeline

688 total, page 7 of 14

COMPLETED NA

Ensuring Patients' Informed Access to Noninvasive Prenatal Testing

NCT03420274

TERMINATED NA

A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis

NCT03442400

COMPLETED

Can Sleep Apnea Screening Questionnaire Predict Adverse Events in Endoscopic Studies

NCT03436381

COMPLETED

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

NCT03431896

COMPLETED

Applying Nutrient Drink Test in Understanding Pathophysiology of CVS

NCT03470181

COMPLETED

Follow-up of Arthrosurface HemiCAP Implants

NCT03247335

COMPLETED NA

Computer-Assisted Rehabilitation Environment Training After Argus Retinal Prosthesis

NCT03444961

COMPLETED NA

Optimization of Pre-operative Oral Analgesics in Patients Undergoing Ambulatory Minimally Invasive Hysterectomy

NCT03420794

COMPLETED

A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery

NCT03413449

COMPLETED NA

Title: Randomized Trial of an EHR Embedded Risk Calculator vs. Standard VTE Prophylaxis for Medical Patients

NCT03243708

COMPLETED NA

Measuring the Impact of an Interactive Communication Skills Curriculum on Internal Medicine Residents

NCT05057780

COMPLETED Phase 4

Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular

NCT03322657

COMPLETED NA

Gilenya's Impact on Cognitive Function and Thalamic Volumes

NCT03243721

COMPLETED Phase 4

Study of Ketorolac Versus Opioid for Pain After Endoscopy

NCT03888144

COMPLETED NA

A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery

NCT03319277

COMPLETED

Biomarker Database Registry for Photodynamic Therapy

NCT03319251

TERMINATED NA

Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA)

NCT03260699

COMPLETED Phase 2

Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT

NCT03283566

COMPLETED Phase 4

Ancillary Effects of Oral Naloxegol (Movantik)

NCT03235739

COMPLETED NA

The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty

NCT03285529

COMPLETED NA

Prospective Randomized Trial of Stratafix vs. Vicryl in Total Hip Arthroplasty.

NCT03285555

COMPLETED NA

Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty

NCT03285542

COMPLETED

Wearable Technology in Shoulder Range of Motion

NCT03195751

COMPLETED NA

Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM

NCT03283982

COMPLETED NA

Telescopic Dissection vs. Balloon Dissection During Laparoscopic TEP Inguinal Hernia Repair

NCT03276871

COMPLETED NA

Pulmonary Vein Isolation in Athletes

NCT03226847

COMPLETED NA

Effect of an Opioid Disposal Pouch Versus Usual Care on Post Discharge Disposal of Unused Medication

NCT04553588

TERMINATED NA

Survey of QRS Frequency at Various Left Ventricular Pacing Sites for Cardiac Resynchronization

NCT03253809

TERMINATED

Sensitivity of Extended Cultures in Diagnosing Urinary Tract Infections

NCT03080389

COMPLETED NA

Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery

NCT05853250

COMPLETED NA

Accuracy of Commercially Available Heart Rate Monitors III

NCT03182439

COMPLETED

Conduction Abnormalities With Severe Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement

NCT03180073

COMPLETED NA

Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide

NCT03016572

COMPLETED Phase 2

Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?

NCT03338400

COMPLETED NA

Vasopressin in Intraabdominal Pressure Elevation

NCT03707054

TERMINATED

Bypass vs. Ecmo in Lung Transplantation (BELT)

NCT03021538

COMPLETED NA

Lifestyle Education and Nutrition Demonstration

NCT03095768

COMPLETED NA

Comparison of Usual Care and Distraction (Tablet) in Children 3-5 Years Old

NCT05368961

COMPLETED

Ultrasonographic Identification of the Proximal Humerus Landmarks

NCT03121794

COMPLETED NA

Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery

NCT03111875

COMPLETED

Functional Capacity and Quality of Life Following Septal Myectomy in Patients With HCM

NCT03092843

COMPLETED NA

Heavy Weight Versus Medium Weight Mesh in Ventral Hernia Repair

NCT03082391

COMPLETED

SEEG Investigation of Mood Dysregulation in Epilepsy

NCT03097809

COMPLETED NA

A Social Media Intervention for Exercise Motivation and Cardiac Rehabilitation Adherence

NCT02971813

COMPLETED NA

Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse

NCT03005977

COMPLETED NA

Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis

NCT03070210

COMPLETED NA

Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery

NCT03048682

TERMINATED Phase 4

CARAT: Canagliflozin vs. Placebo for Post Bariatric Patients With Persistent Type 2 Diabetes

NCT02912455

COMPLETED NA

Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA)

NCT03044028

TERMINATED Phase 4

The Role of F-18 Florbetapir in the Early Detection of Cardiac Amyloidosis

NCT03040427

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Phase Distribution

PhaseTrial count
Phase 1 38
Phase 2 38
Phase 3 22
Phase 4 59

What the Pipeline for The Cleveland Clinic Shows

According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.

The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.