The Cleveland Clinic
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).
The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Top-decile sponsor footprint
The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
688 total, page 7 of 14
Ensuring Patients' Informed Access to Noninvasive Prenatal Testing
NCT03420274
A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis
NCT03442400
Can Sleep Apnea Screening Questionnaire Predict Adverse Events in Endoscopic Studies
NCT03436381
Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis
NCT03431896
Applying Nutrient Drink Test in Understanding Pathophysiology of CVS
NCT03470181
Follow-up of Arthrosurface HemiCAP Implants
NCT03247335
Computer-Assisted Rehabilitation Environment Training After Argus Retinal Prosthesis
NCT03444961
Optimization of Pre-operative Oral Analgesics in Patients Undergoing Ambulatory Minimally Invasive Hysterectomy
NCT03420794
A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery
NCT03413449
Title: Randomized Trial of an EHR Embedded Risk Calculator vs. Standard VTE Prophylaxis for Medical Patients
NCT03243708
Measuring the Impact of an Interactive Communication Skills Curriculum on Internal Medicine Residents
NCT05057780
Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular
NCT03322657
Gilenya's Impact on Cognitive Function and Thalamic Volumes
NCT03243721
Study of Ketorolac Versus Opioid for Pain After Endoscopy
NCT03888144
A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery
NCT03319277
Biomarker Database Registry for Photodynamic Therapy
NCT03319251
Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA)
NCT03260699
Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT
NCT03283566
Ancillary Effects of Oral Naloxegol (Movantik)
NCT03235739
The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty
NCT03285529
Prospective Randomized Trial of Stratafix vs. Vicryl in Total Hip Arthroplasty.
NCT03285555
Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty
NCT03285542
Wearable Technology in Shoulder Range of Motion
NCT03195751
Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
NCT03283982
Telescopic Dissection vs. Balloon Dissection During Laparoscopic TEP Inguinal Hernia Repair
NCT03276871
Pulmonary Vein Isolation in Athletes
NCT03226847
Effect of an Opioid Disposal Pouch Versus Usual Care on Post Discharge Disposal of Unused Medication
NCT04553588
Survey of QRS Frequency at Various Left Ventricular Pacing Sites for Cardiac Resynchronization
NCT03253809
Sensitivity of Extended Cultures in Diagnosing Urinary Tract Infections
NCT03080389
Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery
NCT05853250
Accuracy of Commercially Available Heart Rate Monitors III
NCT03182439
Conduction Abnormalities With Severe Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement
NCT03180073
Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide
NCT03016572
Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
NCT03338400
Vasopressin in Intraabdominal Pressure Elevation
NCT03707054
Bypass vs. Ecmo in Lung Transplantation (BELT)
NCT03021538
Lifestyle Education and Nutrition Demonstration
NCT03095768
Comparison of Usual Care and Distraction (Tablet) in Children 3-5 Years Old
NCT05368961
Ultrasonographic Identification of the Proximal Humerus Landmarks
NCT03121794
Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
NCT03111875
Functional Capacity and Quality of Life Following Septal Myectomy in Patients With HCM
NCT03092843
Heavy Weight Versus Medium Weight Mesh in Ventral Hernia Repair
NCT03082391
SEEG Investigation of Mood Dysregulation in Epilepsy
NCT03097809
A Social Media Intervention for Exercise Motivation and Cardiac Rehabilitation Adherence
NCT02971813
Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse
NCT03005977
Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis
NCT03070210
Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery
NCT03048682
CARAT: Canagliflozin vs. Placebo for Post Bariatric Patients With Persistent Type 2 Diabetes
NCT02912455
Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA)
NCT03044028
The Role of F-18 Florbetapir in the Early Detection of Cardiac Amyloidosis
NCT03040427
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What is open in the The Cleveland Clinic pipeline
99 recruiting of 688 indexed (14% open); 437 completed (64%).
Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).
Top condition: Atrial Fibrillation (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
The Cleveland Clinic: open-pipeline peers nationwide
Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 688 trials (± recruiting share)
- Vanderbilt University Medical Center · 677 trials · 19% recruiting
- Weill Medical College of Cornell University · 701 trials · 18% recruiting
- Icahn School of Medicine at Mount Sinai · 708 trials · 23% recruiting
- Sanofi · 713 trials · 10% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Dana-Farber Cancer Institute · 14% recruiting · 781 trials
- ModernaTX · 14% recruiting · 90 trials
- Masonic Cancer Center, University of Minnesota · 14% recruiting · 249 trials
- Academic and Community Cancer Research United · 14% recruiting · 42 trials
Related
What to do with this The Cleveland Clinic page
688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.
- 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. The Cleveland Clinic pipeline card: 688 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.