The Cleveland Clinic
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Trial Pipeline
688 total, page 7 of 14
Ensuring Patients' Informed Access to Noninvasive Prenatal Testing
NCT03420274
A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis
NCT03442400
Can Sleep Apnea Screening Questionnaire Predict Adverse Events in Endoscopic Studies
NCT03436381
Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis
NCT03431896
Applying Nutrient Drink Test in Understanding Pathophysiology of CVS
NCT03470181
Follow-up of Arthrosurface HemiCAP Implants
NCT03247335
Computer-Assisted Rehabilitation Environment Training After Argus Retinal Prosthesis
NCT03444961
Optimization of Pre-operative Oral Analgesics in Patients Undergoing Ambulatory Minimally Invasive Hysterectomy
NCT03420794
A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery
NCT03413449
Title: Randomized Trial of an EHR Embedded Risk Calculator vs. Standard VTE Prophylaxis for Medical Patients
NCT03243708
Measuring the Impact of an Interactive Communication Skills Curriculum on Internal Medicine Residents
NCT05057780
Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular
NCT03322657
Gilenya's Impact on Cognitive Function and Thalamic Volumes
NCT03243721
Study of Ketorolac Versus Opioid for Pain After Endoscopy
NCT03888144
A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery
NCT03319277
Biomarker Database Registry for Photodynamic Therapy
NCT03319251
Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA)
NCT03260699
Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT
NCT03283566
Ancillary Effects of Oral Naloxegol (Movantik)
NCT03235739
The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty
NCT03285529
Prospective Randomized Trial of Stratafix vs. Vicryl in Total Hip Arthroplasty.
NCT03285555
Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty
NCT03285542
Wearable Technology in Shoulder Range of Motion
NCT03195751
Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
NCT03283982
Telescopic Dissection vs. Balloon Dissection During Laparoscopic TEP Inguinal Hernia Repair
NCT03276871
Pulmonary Vein Isolation in Athletes
NCT03226847
Effect of an Opioid Disposal Pouch Versus Usual Care on Post Discharge Disposal of Unused Medication
NCT04553588
Survey of QRS Frequency at Various Left Ventricular Pacing Sites for Cardiac Resynchronization
NCT03253809
Sensitivity of Extended Cultures in Diagnosing Urinary Tract Infections
NCT03080389
Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery
NCT05853250
Accuracy of Commercially Available Heart Rate Monitors III
NCT03182439
Conduction Abnormalities With Severe Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement
NCT03180073
Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide
NCT03016572
Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
NCT03338400
Vasopressin in Intraabdominal Pressure Elevation
NCT03707054
Bypass vs. Ecmo in Lung Transplantation (BELT)
NCT03021538
Lifestyle Education and Nutrition Demonstration
NCT03095768
Comparison of Usual Care and Distraction (Tablet) in Children 3-5 Years Old
NCT05368961
Ultrasonographic Identification of the Proximal Humerus Landmarks
NCT03121794
Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
NCT03111875
Functional Capacity and Quality of Life Following Septal Myectomy in Patients With HCM
NCT03092843
Heavy Weight Versus Medium Weight Mesh in Ventral Hernia Repair
NCT03082391
SEEG Investigation of Mood Dysregulation in Epilepsy
NCT03097809
A Social Media Intervention for Exercise Motivation and Cardiac Rehabilitation Adherence
NCT02971813
Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse
NCT03005977
Clinical Trial to Evaluate the Endoscopic Ultrasound Guided Celiac Plexus Block for Treatment of Pain in Chronic Pancreatitis
NCT03070210
Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery
NCT03048682
CARAT: Canagliflozin vs. Placebo for Post Bariatric Patients With Persistent Type 2 Diabetes
NCT02912455
Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA)
NCT03044028
The Role of F-18 Florbetapir in the Early Detection of Cardiac Amyloidosis
NCT03040427
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What the Pipeline for The Cleveland Clinic Shows
According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.
The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.