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NCT03442400 · ClinicalTrials.gov registry record · NA

A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis

A NA study, sponsored by The Cleveland Clinic.

Terminated
Registry status
NA
Development phase
5
Enrollment target

NCT03442400 is a NA study that was terminated before completion, run by The Cleveland Clinic. The registered enrollment target is 5 participants.

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The verdict

NCT03442400, a NA study, was terminated before completion, sponsored by The Cleveland Clinic.

TERMINATED
Registry status
NA
Development phase
5 participants
Enrollment target

Study Summary

Coronary artery blockages can reduce blood flow to the heart muscle. Fractional flow reserve (iFR or FFR) assessment is an invasive tool used to determine how much blood flow is reduced. The investigators will perform iFR/FFR on all intermediate coronary stenoses using standard practice, immediately before (at the time of) transcatheter aortic valve replacement (TAVR) and after successful TAVR. The investigators will compare pre- and post-TAVR iFR/FFR values, and assess short-term outcomes. The investigators hypothesize that iFR/FFR values will be consistently and significantly higher pre-TAVR in comparison with post-TAVR for the same lesions.

Interventions

  • DEVICE Volcano iFR/FFR Verrata Plus coronary pressure/flow wire

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2018-02-14
Est. Completion 2021-08-10
Phase NA

Sponsor

The Cleveland Clinic

688 total trials

What the Registry Record Tells You About NCT03442400

The ClinicalTrials.gov registry entry for NCT03442400 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Volcano iFR/FFR Verrata Plus coronary pressure/flow wire is the first listed.

NCT03442400 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03442400 about?

NCT03442400 is a clinical study titled "A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis". Coronary artery blockages can reduce blood flow to the heart muscle. Fractional flow reserve (iFR or FFR) assessment is an invasive tool used to determine how much blood flow is reduced. The investigators will perform iFR/FFR on all intermediate coronary stenoses using standard practice, immediately...

What is the current status of trial NCT03442400?

This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2018-02-14. Estimated completion is 2021-08-10.

What interventions are being tested in trial NCT03442400?

The interventions under investigation include: Volcano iFR/FFR Verrata Plus coronary pressure/flow wire (DEVICE).

Who is sponsoring clinical trial NCT03442400?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.