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NCT03283566 · ClinicalTrials.gov registry record · Phase 2

Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT

A Phase 2 study of Chronic Pancreatitis and Insulin Dependent Diabetes, sponsored by The Cleveland Clinic.

Completed
Registry status
Phase 2
Development phase
9
Enrollment target
1
Study location

NCT03283566 is a Phase 2 study of Chronic Pancreatitis and Insulin Dependent Diabetes that has completed, run by The Cleveland Clinic. The registered enrollment target is 9 participants, below the 689-participant average among 42 other Chronic Pancreatitis trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03283566, a Phase 2 study of Chronic Pancreatitis and Insulin Dependent Diabetes, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
Phase 2
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

This will be a pilot, 12-month phase II, open label, randomized, two-arm, single-blinded, placebo-controlled, parallel clinical trial of individuals undergoing TPAIT (Total Pancreatectomy and Autologous Islet Transplantation) for treatment of chronic pancreatitis (CP). The two study arms consist of HCQ-treated (Hydroxychloroquine) and placebo-treated individuals. The purpose of this study is to investigate the effects of HCQ administration compared to placebo on islet cell function post-autologous transplantation.

Interventions

  • DRUG Placebo
  • DRUG Hydroxychloroquine

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2017-10-03
Est. Completion 2020-05-31
Phase Phase 2

Sponsor

The Cleveland Clinic

688 total trials

What the Registry Record Tells You About NCT03283566

The ClinicalTrials.gov registry entry for NCT03283566 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 689-participant average among 42 other Chronic Pancreatitis trials with a reported enrollment target (99% lower). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Chronic Pancreatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03283566 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT03283566 about?

NCT03283566 is a clinical study titled "Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT". This will be a pilot, 12-month phase II, open label, randomized, two-arm, single-blinded, placebo-controlled, parallel clinical trial of individuals undergoing TPAIT (Total Pancreatectomy and Autologous Islet Transplantation) for treatment of chronic pancreatitis (CP). The two study arms consist of ...

What is the current status of trial NCT03283566?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2017-10-03. Estimated completion is 2020-05-31.

What conditions does trial NCT03283566 study?

This clinical trial studies the following conditions: Chronic Pancreatitis, Insulin Dependent Diabetes.

What interventions are being tested in trial NCT03283566?

The interventions under investigation include: Placebo (DRUG), Hydroxychloroquine (DRUG).

Who is sponsoring clinical trial NCT03283566?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03283566 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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