The Cleveland Clinic

688 total trials 99 currently recruiting 437 completed

The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.

Trial Pipeline

688 total, page 8 of 14

COMPLETED

Biomarkers as Predictors of Suicidal Risk in Adolescents

NCT03014518

COMPLETED NA

Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine

NCT02996227

TERMINATED

Survivorship, Radiographic, and Functional Outcomes of the Multihole Revision Acetabular Cup

NCT03031964

COMPLETED

Vasopressin Plasma Concentrations in Patients Receiving Exogenous Vasopressin Infusion for Septic Shock

NCT03014063

COMPLETED Phase 4

Bupivacaine Liposomal Injection (Exparel) for Postsurgical Analgesia in Patient Undergoing Laparoscopic Bariatric Surgery

NCT02969187

COMPLETED NA

Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology

NCT02853591

COMPLETED NA

Noninvasive Beat-to-Beat ClearSight Blood Pressure Monitoring

NCT02872896

COMPLETED NA

Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans

NCT03039023

COMPLETED NA

Functional Medicine in Asthma (FAst) Study

NCT02808689

COMPLETED

Mild Acute Ischemic Stroke With Large Vessel Occlusion (MISTWAVE)

NCT03731351

COMPLETED NA

Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)

NCT02909907

COMPLETED

Superior Vena Cava and Its Relationship to Central Venous Pressure Measurements in Liver Transplantation

NCT02818218

COMPLETED

Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma

NCT02897128

COMPLETED NA

Ocular Sarcoidosis Open Label Trial of ACTHAR Gel

NCT02725177

COMPLETED NA

Home Monitoring After Primary Total Knee Arthroplasty

NCT03032068

COMPLETED NA

Human Pilot Study - HA35 (Hyaluronan Molecular Weight 35) Dietary Supplement for Promoting Intestinal Health

NCT02867605

COMPLETED NA

Evaluation of Spine Surgery Analgesic Pathway

NCT02887404

COMPLETED NA

Dedicated Ambulator-assisted Physical Activity to Improve Hospital Outcome Measures in Elderly Patients

NCT02757131

COMPLETED NA

Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their Parents

NCT02857543

COMPLETED NA

Endothelial Function After Cardiac Surgery

NCT02882074

TERMINATED NA

Intraoperative Ultrasound in Laparoscopic or Robotic Myomectomy Patients

NCT02879058

TERMINATED Phase 4

Catheter Ablation vs. Medical Therapy in Congested Hearts With AF

NCT02686749

COMPLETED NA

The Role of the Robotic Platform in Inguinal Hernia Repair Surgery

NCT02816658

COMPLETED NA

Evaluating Heat Transfer With the Esophageal Cooling Device

NCT02743884

COMPLETED NA

Fluorescent Cholangiography vs White Light for Bile Ducts Identification

NCT02702843

COMPLETED NA

My Recordable On-Demand Audio Discharge Instructions

NCT02901314

COMPLETED NA

Comparison of Vaginal Laser Therapy to Vaginal Estrogen Therapy

NCT02691936

COMPLETED

Carpal Tunnel Syndrome and Amyloid Cardiomyopathy

NCT02792790

COMPLETED Early Phase 1

Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity

NCT03020433

COMPLETED NA

Effects of Continuous Bilateral QL Analgesia After Open Abdominal Surgery

NCT02684968

COMPLETED NA

Groin Wound Infection Rate Using Prevena Compared to Standard Dressing in Vascular Surgery Patients With High Risk

NCT03105154

COMPLETED Phase 4

Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management

NCT04284930

TERMINATED NA

Postoperative Acute Myocardial Ischemic Injury

NCT02993263

TERMINATED NA

Frequency of Reduced Leaflet Motion After Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement.

NCT02696226

COMPLETED NA

Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores

NCT02840240

COMPLETED Phase 2

A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation

NCT02544113

COMPLETED NA

Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study

NCT02643316

TERMINATED Phase 1

An Exploratory Trial of Ketamine for the Treatment of Rett Syndrome

NCT02562820

COMPLETED NA

Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial

NCT02565420

COMPLETED NA

The Effects of Dual Task Training in Individuals With Parkinson's Disease

NCT02538029

COMPLETED NA

Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression

NCT02522377

COMPLETED NA

Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery

NCT02509260

COMPLETED NA

Forced Aerobic Exercise for Stroke Rehabilitation

NCT02494518

TERMINATED Phase 4

Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac Surgery

NCT02291419

COMPLETED Phase 4

Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis

NCT02245841

COMPLETED

Evaluating the Validity of an Eye Gaze Paradigm in Predicting Autism Spectrum Disorder

NCT02573428

COMPLETED NA

Do Arterial Catheters Reduce the Risk of Major Perioperative Complications

NCT02453815

TERMINATED NA

Intraoperative Anesthesia Care Transition Checklist

NCT02453828

COMPLETED Phase 2

Rasagiline Rescue in Alzheimer's Disease Clinical Trial

NCT02359552

COMPLETED NA

Intra-vaginal Electrical Stimulation Device Compared to Sham Device for Chronic Pelvic Pain

NCT02397785

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Phase Distribution

PhaseTrial count
Phase 1 38
Phase 2 38
Phase 3 22
Phase 4 59

What the Pipeline for The Cleveland Clinic Shows

According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.

The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.