The Cleveland Clinic
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).
The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Top-decile sponsor footprint
The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
688 total, page 8 of 14
Biomarkers as Predictors of Suicidal Risk in Adolescents
NCT03014518
Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine
NCT02996227
Survivorship, Radiographic, and Functional Outcomes of the Multihole Revision Acetabular Cup
NCT03031964
Vasopressin Plasma Concentrations in Patients Receiving Exogenous Vasopressin Infusion for Septic Shock
NCT03014063
Bupivacaine Liposomal Injection (Exparel) for Postsurgical Analgesia in Patient Undergoing Laparoscopic Bariatric Surgery
NCT02969187
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
NCT02853591
Noninvasive Beat-to-Beat ClearSight Blood Pressure Monitoring
NCT02872896
Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans
NCT03039023
Functional Medicine in Asthma (FAst) Study
NCT02808689
Mild Acute Ischemic Stroke With Large Vessel Occlusion (MISTWAVE)
NCT03731351
Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)
NCT02909907
Superior Vena Cava and Its Relationship to Central Venous Pressure Measurements in Liver Transplantation
NCT02818218
Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma
NCT02897128
Ocular Sarcoidosis Open Label Trial of ACTHAR Gel
NCT02725177
Home Monitoring After Primary Total Knee Arthroplasty
NCT03032068
Human Pilot Study - HA35 (Hyaluronan Molecular Weight 35) Dietary Supplement for Promoting Intestinal Health
NCT02867605
Evaluation of Spine Surgery Analgesic Pathway
NCT02887404
Dedicated Ambulator-assisted Physical Activity to Improve Hospital Outcome Measures in Elderly Patients
NCT02757131
Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their Parents
NCT02857543
Endothelial Function After Cardiac Surgery
NCT02882074
Intraoperative Ultrasound in Laparoscopic or Robotic Myomectomy Patients
NCT02879058
Catheter Ablation vs. Medical Therapy in Congested Hearts With AF
NCT02686749
The Role of the Robotic Platform in Inguinal Hernia Repair Surgery
NCT02816658
Evaluating Heat Transfer With the Esophageal Cooling Device
NCT02743884
Fluorescent Cholangiography vs White Light for Bile Ducts Identification
NCT02702843
My Recordable On-Demand Audio Discharge Instructions
NCT02901314
Comparison of Vaginal Laser Therapy to Vaginal Estrogen Therapy
NCT02691936
Carpal Tunnel Syndrome and Amyloid Cardiomyopathy
NCT02792790
Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity
NCT03020433
Effects of Continuous Bilateral QL Analgesia After Open Abdominal Surgery
NCT02684968
Groin Wound Infection Rate Using Prevena Compared to Standard Dressing in Vascular Surgery Patients With High Risk
NCT03105154
Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
NCT04284930
Postoperative Acute Myocardial Ischemic Injury
NCT02993263
Frequency of Reduced Leaflet Motion After Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement.
NCT02696226
Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
NCT02840240
A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation
NCT02544113
Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study
NCT02643316
An Exploratory Trial of Ketamine for the Treatment of Rett Syndrome
NCT02562820
Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial
NCT02565420
The Effects of Dual Task Training in Individuals With Parkinson's Disease
NCT02538029
Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression
NCT02522377
Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
NCT02509260
Forced Aerobic Exercise for Stroke Rehabilitation
NCT02494518
Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac Surgery
NCT02291419
Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis
NCT02245841
Evaluating the Validity of an Eye Gaze Paradigm in Predicting Autism Spectrum Disorder
NCT02573428
Do Arterial Catheters Reduce the Risk of Major Perioperative Complications
NCT02453815
Intraoperative Anesthesia Care Transition Checklist
NCT02453828
Rasagiline Rescue in Alzheimer's Disease Clinical Trial
NCT02359552
Intra-vaginal Electrical Stimulation Device Compared to Sham Device for Chronic Pelvic Pain
NCT02397785
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What is open in the The Cleveland Clinic pipeline
99 recruiting of 688 indexed (14% open); 437 completed (64%).
Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).
Top condition: Atrial Fibrillation (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
The Cleveland Clinic: open-pipeline peers nationwide
Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 688 trials (± recruiting share)
- Vanderbilt University Medical Center · 677 trials · 19% recruiting
- Weill Medical College of Cornell University · 701 trials · 18% recruiting
- Icahn School of Medicine at Mount Sinai · 708 trials · 23% recruiting
- Sanofi · 713 trials · 10% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Dana-Farber Cancer Institute · 14% recruiting · 781 trials
- ModernaTX · 14% recruiting · 90 trials
- Masonic Cancer Center, University of Minnesota · 14% recruiting · 249 trials
- Academic and Community Cancer Research United · 14% recruiting · 42 trials
Related
What to do with this The Cleveland Clinic page
688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.
- 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. The Cleveland Clinic pipeline card: 688 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.