The Cleveland Clinic
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Trial Pipeline
688 total, page 8 of 14
Biomarkers as Predictors of Suicidal Risk in Adolescents
NCT03014518
Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine
NCT02996227
Survivorship, Radiographic, and Functional Outcomes of the Multihole Revision Acetabular Cup
NCT03031964
Vasopressin Plasma Concentrations in Patients Receiving Exogenous Vasopressin Infusion for Septic Shock
NCT03014063
Bupivacaine Liposomal Injection (Exparel) for Postsurgical Analgesia in Patient Undergoing Laparoscopic Bariatric Surgery
NCT02969187
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
NCT02853591
Noninvasive Beat-to-Beat ClearSight Blood Pressure Monitoring
NCT02872896
Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans
NCT03039023
Functional Medicine in Asthma (FAst) Study
NCT02808689
Mild Acute Ischemic Stroke With Large Vessel Occlusion (MISTWAVE)
NCT03731351
Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)
NCT02909907
Superior Vena Cava and Its Relationship to Central Venous Pressure Measurements in Liver Transplantation
NCT02818218
Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma
NCT02897128
Ocular Sarcoidosis Open Label Trial of ACTHAR Gel
NCT02725177
Home Monitoring After Primary Total Knee Arthroplasty
NCT03032068
Human Pilot Study - HA35 (Hyaluronan Molecular Weight 35) Dietary Supplement for Promoting Intestinal Health
NCT02867605
Evaluation of Spine Surgery Analgesic Pathway
NCT02887404
Dedicated Ambulator-assisted Physical Activity to Improve Hospital Outcome Measures in Elderly Patients
NCT02757131
Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their Parents
NCT02857543
Endothelial Function After Cardiac Surgery
NCT02882074
Intraoperative Ultrasound in Laparoscopic or Robotic Myomectomy Patients
NCT02879058
Catheter Ablation vs. Medical Therapy in Congested Hearts With AF
NCT02686749
The Role of the Robotic Platform in Inguinal Hernia Repair Surgery
NCT02816658
Evaluating Heat Transfer With the Esophageal Cooling Device
NCT02743884
Fluorescent Cholangiography vs White Light for Bile Ducts Identification
NCT02702843
My Recordable On-Demand Audio Discharge Instructions
NCT02901314
Comparison of Vaginal Laser Therapy to Vaginal Estrogen Therapy
NCT02691936
Carpal Tunnel Syndrome and Amyloid Cardiomyopathy
NCT02792790
Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity
NCT03020433
Effects of Continuous Bilateral QL Analgesia After Open Abdominal Surgery
NCT02684968
Groin Wound Infection Rate Using Prevena Compared to Standard Dressing in Vascular Surgery Patients With High Risk
NCT03105154
Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
NCT04284930
Postoperative Acute Myocardial Ischemic Injury
NCT02993263
Frequency of Reduced Leaflet Motion After Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement.
NCT02696226
Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
NCT02840240
A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation
NCT02544113
Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study
NCT02643316
An Exploratory Trial of Ketamine for the Treatment of Rett Syndrome
NCT02562820
Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial
NCT02565420
The Effects of Dual Task Training in Individuals With Parkinson's Disease
NCT02538029
Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression
NCT02522377
Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
NCT02509260
Forced Aerobic Exercise for Stroke Rehabilitation
NCT02494518
Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac Surgery
NCT02291419
Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis
NCT02245841
Evaluating the Validity of an Eye Gaze Paradigm in Predicting Autism Spectrum Disorder
NCT02573428
Do Arterial Catheters Reduce the Risk of Major Perioperative Complications
NCT02453815
Intraoperative Anesthesia Care Transition Checklist
NCT02453828
Rasagiline Rescue in Alzheimer's Disease Clinical Trial
NCT02359552
Intra-vaginal Electrical Stimulation Device Compared to Sham Device for Chronic Pelvic Pain
NCT02397785
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What the Pipeline for The Cleveland Clinic Shows
According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.
The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.