St. Jude Children's Research Hospital
St. Jude Children's Research Hospital sponsors 410 registered US clinical trials on ClinicalTrials.gov, 90 of them currently recruiting, and 227 completed. 19 of these trials are in Phase 3-4 (later-stage) and 173 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 17 trials.
Trial Pipeline
410 total, page 3 of 9
Evaluating Immune Response to COVID-19 Vaccines in Patients With Cancer, Transplant or Cellular Therapy Recipients
NCT05164016
An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer
NCT04733534
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
NCT04742751
Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
NCT04898894
Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)
NCT03597594
Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis
NCT04551131
Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance
NCT04714840
Social Experiences of Adolescents and Young Adults With Cancer
NCT04328350
Estimating Setup Uncertainty in Pediatric Proton Therapy Using Volumetric Images
NCT04125095
Patient-Reported Outcome Version of the Common Criteria for Adverse Events
NCT04050072
Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
NCT04105530
18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma
NCT03541720
Exploring Adherence Monitoring in Sickle Cell Disease
NCT03708731
TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies
NCT03849651
Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17
NCT03755804
Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia
NCT03573700
Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation
NCT03361020
Next Generation Pathogen Sequencing for Prediction of Adverse Events
NCT03226158
Evaluation of Proton Therapy in Pediatric Cancer Patients
NCT03223766
Social Emotional Development in Young Children With Cancer
NCT03086421
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT03164057
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma
NCT03117751
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
NCT02790515
A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection
NCT02792582
Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I
NCT02553460
A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer
NCT02256137
Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors
NCT02114229
A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma
NCT02125786
Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors
NCT01946529
Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy
NCT01871766
Adcetris (Brentuximab Vedotin), Combination Chemotherapy, and Radiation Therapy in Treating Younger Patients With Stage IIB, IIIB and IV Hodgkin Lymphoma
NCT01920932
Therapy for Children With Advanced Stage Neuroblastoma
NCT01857934
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
NCT01878617
Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma
NCT01783535
A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection
NCT01419067
Mature B-Cell Lymphoma And Leukemia Study III
NCT01046825
Dose-Escalation Study Of A Self Complementary Adeno-Associated Viral Vector For Gene Transfer in Hemophilia B
NCT00979238
Methionine PET/CT Studies In Patients With Cancer
NCT00840047
Stress, Adjustment And Growth In Children With Cancer And Their Parents
NCT01044160
Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Favorable-Risk Hodgkin Lymphoma
NCT00846742
Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma
NCT00539591
Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
NCT00602667
Radiation Therapy to Treat Musculoskeletal Tumors
NCT00186992
Muscle Aging Phenotypes in Childhood Cancer Survivors
NCT07531498
Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease
NCT07616154
Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma
NCT07514819
Real World Asparaginase Therapy Toxicity
NCT07008027
Insights From Bereaved Parents and Oncologists
NCT07663539
Liver Biopsy Following Gene Therapy For Hemophilia
NCT05932914
Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in SJLIFE
NCT07594392
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 87 |
| Phase 2 | 86 |
| Phase 3 | 17 |
| Phase 4 | 2 |
Therapeutic Areas
What the Pipeline for St. Jude Children's Research Hospital Shows
According to the ClinicalTrials.gov registry, St. Jude Children's Research Hospital is linked to 410 US clinical trials across every stage of research activity. Of those, 90 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 227 are already marked complete, representing roughly 55% of the total.
The phase mix for St. Jude Children's Research Hospital reports 19 late-stage studies (Phase 3 and Phase 4 combined) and 173 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for St. Jude Children's Research Hospital is Sickle Cell Disease with 17 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.