St. Jude Children's Research Hospital

410 total trials 90 currently recruiting 227 completed

St. Jude Children's Research Hospital sponsors 410 registered US clinical trials on ClinicalTrials.gov, 90 of them currently recruiting, and 227 completed. 19 of these trials are in Phase 3-4 (later-stage) and 173 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 17 trials.

Trial Pipeline

410 total, page 2 of 9

RECRUITING Phase 2

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

NCT05583721

RECRUITING NA

Implementing an Adolescent and Young Adult (AYA) mHealth Vaping Cessation Program Into Oncology Clinics

NCT05967585

RECRUITING NA

Writing Intervention With Adolescents and Young Adults With Cancer

NCT05975333

RECRUITING Phase 2

Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus Infections After Hematopoietic Cell Transplantation

NCT05664126

RECRUITING NA

Cognitive Training in the Virtual Reality Setting With Children Undergoing Radiotherapy for Brain Tumors

NCT05947045

RECRUITING

Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

NCT05810181

RECRUITING Phase 1

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

NCT05835687

RECRUITING

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

NCT05480904

RECRUITING

Childhood Cancer Survivors' Affective Response to Exercise

NCT05763290

RECRUITING

Long-term Follow-up After Adoptive Transfer of Genetically Modified Cell Products

NCT05713214

RECRUITING Phase 2

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

NCT05535166

RECRUITING Phase 1

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

NCT05468359

RECRUITING

Response to Influenza Vaccination in Pediatric Oncology Patients

NCT05384288

RECRUITING

The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network

NCT05454618

RECRUITING

Discarded Bone Marrow for Hematology Research

NCT04671212

RECRUITING Phase 1

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT04897321

RECRUITING Phase 2

Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation

NCT04968990

RECRUITING Phase 1

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

NCT04923126

RECRUITING Phase 1

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

NCT04901702

RECRUITING NA

Study Of Cold Cap Therapy For Prevention of Hairloss in Pediatric Patients Receiving Chemotherapy For Non-Malignant Indications and Solid Tumors

NCT04764357

RECRUITING Phase 2

Haploidentical HCT for Severe Aplastic Anemia

NCT04558736

RECRUITING

Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

NCT04416178

RECRUITING Phase 1

Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

NCT04195347

RECRUITING Phase 1

CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

NCT04318678

RECRUITING

Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coronavirus 2019 (COVID-19) In Children

NCT04371315

RECRUITING Phase 1

Indocyanine Green (ICG) Guided Tumor Resection

NCT04084067

RECRUITING NA

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

NCT04065776

RECRUITING NA

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

NCT03353584

RECRUITING

Familial Investigations of Childhood Cancer Predisposition

NCT03050268

RECRUITING

Investigation of the Genetics of Hematologic Diseases

NCT02720679

RECRUITING

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

NCT02775643

RECRUITING

Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients

NCT02530658

RECRUITING

Sickle Cell Clinical Research and Intervention Program

NCT02098863

RECRUITING

Molecular Analysis Of Solid Tumors

NCT01050296

RECRUITING

Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

NCT01354002

RECRUITING

Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer

NCT00760656

RECRUITING

International Pediatric Adrenocortical Tumor Registry

NCT00700414

RECRUITING

Protocol For Collecting Data On Patients With Childhood Cancer

NCT00684580

RECRUITING

Pharmacogenetic Determinants Of Treatment Response In Children

NCT00730678

RECRUITING

Childhood Cancer Survivor Study

NCT01120353

ACTIVE NOT RECRUITING NA

Complementary Behavioral Interventions To Remediate Cognitive Impairment or Emotional Distress in Cancer Survivors

NCT06989463

ACTIVE NOT RECRUITING

Remote Exercise Video Adaptations to Maximize Physical Activity in Childhood Cancer

NCT06411704

ACTIVE NOT RECRUITING NA

Mindfulness Interventions to Improve Health Activation, Coping, and Stress Among Childhood Cancer Survivors

NCT06053268

ACTIVE NOT RECRUITING NA

Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis

NCT05930418

ACTIVE NOT RECRUITING

Patient- Generated Health Data to Predict Childhood Cancer Survivorship Outcomes

NCT05342155

ACTIVE NOT RECRUITING Phase 2

Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms

NCT05656248

ACTIVE NOT RECRUITING NA

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

NCT05550948

ACTIVE NOT RECRUITING

An Evaluation of Concordance of Smartwatch ECG and One Clinical ECG and Comparison of The Two ECGS in Terms of Predictive Risks

NCT05617391

ACTIVE NOT RECRUITING Phase 1

Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax

NCT05192889

ACTIVE NOT RECRUITING Phase 2

Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study

NCT05128903

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 86
Phase 3 17
Phase 4 2

What the Pipeline for St. Jude Children's Research Hospital Shows

According to the ClinicalTrials.gov registry, St. Jude Children's Research Hospital is linked to 410 US clinical trials across every stage of research activity. Of those, 90 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 227 are already marked complete, representing roughly 55% of the total.

The phase mix for St. Jude Children's Research Hospital reports 19 late-stage studies (Phase 3 and Phase 4 combined) and 173 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for St. Jude Children's Research Hospital is Sickle Cell Disease with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.