St. Jude Children's Research Hospital

410 total trials 90 currently recruiting 227 completed

St. Jude Children's Research Hospital sponsors 410 registered US clinical trials on ClinicalTrials.gov, 90 of them currently recruiting, and 227 completed. 19 of these trials are in Phase 3-4 (later-stage) and 173 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 17 trials.

Trial Pipeline

410 total, page 1 of 9

RECRUITING NA

Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors

NCT07516301

RECRUITING NA

Bereaved Parent Conversations on Hope

NCT07675083

RECRUITING

Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients

NCT07502885

RECRUITING

Outcomes of Health Care Transition for AYA With a Cancer Predisposition

NCT07456904

RECRUITING NA

Feasibility of High Intensity Interval Training in Survivors of Childhood, Adolescent, and Young Adult Hodgkin Lymphoma

NCT07222345

RECRUITING

Functional Ovarian Reserve in Sickle Cell Disease

NCT07392216

RECRUITING Phase 2

Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma

NCT07428993

RECRUITING Phase 2

Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

NCT07228741

RECRUITING Phase 2

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

NCT06528691

RECRUITING

Stakeholders of Rare Diseases Informing Values In Neuroethics

NCT07314736

RECRUITING

A Longitudinal Photo-Narrative Exploration of Hope During Phase 1/2 Clinical Trials For Pediatric Cancer

NCT07444216

RECRUITING Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

NCT07257419

RECRUITING NA

Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

NCT07191119

RECRUITING NA

Evaluation Of Cardiovascular Health Outcomes Among Survivors 2

NCT07245420

RECRUITING

CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation

NCT07085325

RECRUITING Phase 1

Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas

NCT07222735

RECRUITING

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

NCT06579469

RECRUITING Phase 1

Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

NCT07226219

RECRUITING Phase 2

A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

NCT07085338

RECRUITING

Exploring the Physiologic, Pharmacodynamic, and Clinical Responses of Skeletal Muscle in Patients With Spinal Muscular Atrophy Treated With SMN-Directed Therapies

NCT06532474

RECRUITING

CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions

NCT07048535

RECRUITING Phase 1

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

NCT07052370

RECRUITING Early Phase 1

Positron Emission Tomography (PET) Contrast Agent Kinetics and Safety: [18F]-Fluoromannitol

NCT07110519

RECRUITING NA

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

NCT07160621

RECRUITING NA

Seminar in Unwavering Empowering Presence Optimized for Rehabilitation Teams

NCT07071116

RECRUITING Phase 1

Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT).

NCT05664113

RECRUITING

Long Term Follow-Up Study for Individuals With Hemoglobin Disorders After Hematopoietic Cell Transplant or Gene Therapy

NCT06646640

RECRUITING NA

Revealing Information Genuinely & Honestly Across Time - Communication Preferences Visit

NCT06993688

RECRUITING NA

Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors

NCT06819475

RECRUITING Phase 1

A Prospective Trial of Dalbavancin-Based Prophylaxis in Children and Adolescents With High-Risk Leukemia

NCT06810583

RECRUITING Phase 2

CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia

NCT06847269

RECRUITING Phase 1

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

NCT06777979

RECRUITING NA

School Readiness Intervention for Preschool Children With Sickle Cell Disease

NCT06367192

RECRUITING Phase 1

Gene Editing For Sickle Cell Disease

NCT06506461

RECRUITING NA

Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma

NCT06747910

RECRUITING Phase 2

Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

NCT06533748

RECRUITING Phase 2

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

NCT06390319

RECRUITING Phase 4

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

NCT06289673

RECRUITING Phase 1

SCD Stem Cell Mobilization and Apheresis Using Motixafortide

NCT06442761

RECRUITING

Feasibility of Screening for Early Late Effects of Contemporary Therapy in High-Risk Neuroblastoma Survivors

NCT06480526

RECRUITING Phase 1

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

NCT06326463

RECRUITING

Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease

NCT06477289

RECRUITING

Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors

NCT06421987

RECRUITING Phase 1

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

NCT06177067

RECRUITING

Patient-Reported Outcomes and Quality of Life in Adult and Pediatric Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma (NLPHL)

NCT06098430

RECRUITING Phase 1

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

NCT06239272

RECRUITING Phase 2

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

NCT06023641

RECRUITING Phase 1

Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

NCT04881240

RECRUITING

Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition

NCT05849155

RECRUITING Early Phase 1

Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid Tumors

NCT05645523

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 86
Phase 3 17
Phase 4 2

What the Pipeline for St. Jude Children's Research Hospital Shows

According to the ClinicalTrials.gov registry, St. Jude Children's Research Hospital is linked to 410 US clinical trials across every stage of research activity. Of those, 90 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 227 are already marked complete, representing roughly 55% of the total.

The phase mix for St. Jude Children's Research Hospital reports 19 late-stage studies (Phase 3 and Phase 4 combined) and 173 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for St. Jude Children's Research Hospital is Sickle Cell Disease with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.