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NCT05930418 · ClinicalTrials.gov registry record · NA
Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis
A NA study of Sepsis and Acute Respiratory Distress Syndrome, sponsored by St. Jude Children's Research Hospital.
- Active
- Registry status
- NA
- Development phase
- 7
- Enrollment target
- 1
- Study location
NCT05930418 is a NA study of Sepsis and Acute Respiratory Distress Syndrome that is active but no longer recruiting, run by St. Jude Children's Research Hospital. The registered enrollment target is 7 participants, below the 6,565-participant average among 90 other Sepsis trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05930418, a NA study of Sepsis and Acute Respiratory Distress Syndrome, is active but no longer recruiting, sponsored by St. Jude Children's Research Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall purpose of this protocol is to identify subacute sepsis-associated cardiac disease in pediatric patients with cancer by CMR and evaluate the CMR findings during their follow-up. This will help inform heart failure management decision making. Evidence of dysfunction or elevated T2 values may inform adjustment of afterload reduction and beta blocker administration, and elevated ECV findings will suggest the need for increased surveillance for diastolic dysfunction. Primary Objectives: (Feasibility Phase) To determine the feasibility of cardiac MRI without anesthesia in the immediate post-sepsis period in children with cancer. CMR scanning will be completed within 10 days of presentation - this will allow us to ensure that possible hemodynamic or respiratory instability and renal dysfunction has resolved prior to transport to the MRI scanner during the most acute phase of illness. (Completion Phase) To estimate the frequency of subacute sepsis-associated cardiac disease, including myocardial inflammation and dysfunction, in the post-acute phase (within 10 days of presentation) of severe sepsis in children with cancer
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Cardiac MRI
Study Locations (1)
Tennessee
- St. Jude Children's Research Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2023-05-20 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05930418
The ClinicalTrials.gov registry entry for NCT05930418 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 6,565-participant average among 90 other Sepsis trials with a reported enrollment target (100% lower). The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Sepsis appearing as the primary indexed condition, and to 1 intervention - of which Cardiac MRI is the first listed.
NCT05930418 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT05930418 about?
NCT05930418 is a clinical study titled "Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis". The overall purpose of this protocol is to identify subacute sepsis-associated cardiac disease in pediatric patients with cancer by CMR and evaluate the CMR findings during their follow-up. This will help inform heart failure management decision making. Evidence of dysfunction or elevated T2 values ...
What is the current status of trial NCT05930418?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 7 participants. The study started on 2023-05-20. Estimated completion is 2027-12-31.
What conditions does trial NCT05930418 study?
This clinical trial studies the following conditions: Sepsis, Acute Respiratory Distress Syndrome, Cardiovascular Shock.
What interventions are being tested in trial NCT05930418?
The interventions under investigation include: Cardiac MRI (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05930418?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05930418 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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