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NCT01050296 · ClinicalTrials.gov registry record
Molecular Analysis Of Solid Tumors
A clinical trial of Pediatric Solid Tumors, sponsored by St. Jude Children's Research Hospital.
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 1
- Study location
NCT01050296 is a study of Pediatric Solid Tumors that is actively recruiting participants, run by St. Jude Children's Research Hospital. The registered enrollment target is 1,000 participants. The trial reports 1 study location across 1 state.
The verdict
NCT01050296, a study of Pediatric Solid Tumors, is actively recruiting participants, sponsored by St. Jude Children's Research Hospital.
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will prospectively characterize the molecular, cellular and genetic properties of primary and metastatic neuroblastoma, osteosarcoma, retinoblastoma, Ewing sarcoma family of tumors, soft tissue sarcomas, adrenocortical tumors and liver malignancies. These cell isolates will be used for gene expression array analysis, genomic analysis by \[SNP\] single nucleotide polymorphism chip, array \[CGH\] comparative genomic hybridization and next generation sequencing, and \[TEM\] transmission electron microscopy analysis. Additionally cell lines and orthotopic xenografts will be created from the obtained tumor specimens. The specificity of TCRs will be examined by comparing paired TCR from peripheral blood and tumor infiltrating CD4+ and CD8+ T cells. Epigenetic studies will be performed looking at the methylation profile of these cells and to investigate the anti-tumor T cell response both pre- and post-PD1 inhibition.
Conditions Studied
Study Locations (1)
Tennessee
- St. Jude Children's Research Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2010-02-10 |
| Est. Completion | 2026-09-30 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01050296
The ClinicalTrials.gov registry entry for NCT01050296 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pediatric Solid Tumors appearing as the primary indexed condition, and to 0 interventions.
NCT01050296 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT01050296 about?
NCT01050296 is a clinical study titled "Molecular Analysis Of Solid Tumors". This study will prospectively characterize the molecular, cellular and genetic properties of primary and metastatic neuroblastoma, osteosarcoma, retinoblastoma, Ewing sarcoma family of tumors, soft tissue sarcomas, adrenocortical tumors and liver malignancies. These cell isolates will be used for ge...
What is the current status of trial NCT01050296?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2010-02-10. Estimated completion is 2026-09-30.
What conditions does trial NCT01050296 study?
This clinical trial studies the following conditions: Pediatric Solid Tumors.
Who is sponsoring clinical trial NCT01050296?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01050296 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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