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NCT01050296 · ClinicalTrials.gov registry record
Molecular Analysis Of Solid Tumors
A clinical trial of Pediatric Solid Tumors, sponsored by St. Jude Children's Research Hospital.
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 1
- Study location
NCT01050296: Recruiting study of Pediatric Solid Tumors, sponsored by St. Jude Children's Research Hospital.
NCT01050296 is a study of Pediatric Solid Tumors that is actively recruiting participants, run by St. Jude Children's Research Hospital. The registered enrollment target is 1,000 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01050296, a study of Pediatric Solid Tumors, is actively recruiting participants, sponsored by St. Jude Children's Research Hospital.
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will prospectively characterize the molecular, cellular and genetic properties of primary and metastatic neuroblastoma, osteosarcoma, retinoblastoma, Ewing sarcoma family of tumors, soft tissue sarcomas, adrenocortical tumors and liver malignancies. These cell isolates will be used for gene expression array analysis, genomic analysis by \[SNP\] single nucleotide polymorphism chip, array \[CGH\] comparative genomic hybridization and next generation sequencing, and \[TEM\] transmission electron microscopy analysis. Additionally cell lines and orthotopic xenografts will be created from the obtained tumor specimens. The specificity of TCRs will be examined by comparing paired TCR from peripheral blood and tumor infiltrating CD4+ and CD8+ T cells. Epigenetic studies will be performed looking at the methylation profile of these cells and to investigate the anti-tumor T cell response both pre- and post-PD1 inhibition.
Conditions Studied
Study Locations (1)
Tennessee
- St. Jude Children's Research Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2010-02-10 |
| Est. Completion | 2026-09-30 |
What NCT01050296 shows while recruiting
NCT01050296 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus.
The record links to 1 condition, with Pediatric Solid Tumors appearing as the primary indexed condition, and to 0 interventions.
NCT01050296 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT01050296 about?
NCT01050296 is a clinical study titled "Molecular Analysis Of Solid Tumors". This study will prospectively characterize the molecular, cellular and genetic properties of primary and metastatic neuroblastoma, osteosarcoma, retinoblastoma, Ewing sarcoma family of tumors, soft tissue sarcomas, adrenocortical tumors and liver malignancies. These cell isolates will be used for ge...
What is the current status of trial NCT01050296?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2010-02-10. Estimated completion is 2026-09-30.
What conditions does trial NCT01050296 study?
This clinical trial studies the following conditions: Pediatric Solid Tumors.
Who is sponsoring clinical trial NCT01050296?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01050296 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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