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NCT00218218 · ClinicalTrials.gov registry record · Phase 2
Effects of Transdermal Nicotine on Smoking, Craving and Withdrawal in People With Schizophrenia
A Phase 2 study, sponsored by National Institute on Drug Abuse (NIDA).
- Completed
- Registry status
- Phase 2
- Development phase
- 48
- Enrollment target
NCT00218218: Completed Phase 2 study, sponsored by National Institute on Drug Abuse (NIDA).
NCT00218218 is a Phase 2 study that has completed, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 48 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00218218, a Phase 2 study, has completed, sponsored by National Institute on Drug Abuse (NIDA).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 48 participants
- Enrollment target
Study Summary
Individuals with schizophrenia are three times as likely to smoke cigarettes as individuals without schizophrenia. While a great deal of research has been focused on smoking cessation programs for healthy individuals, little attention has been directed towards developing an effective smoking cessation treatment for schizophrenics. This project will evaluate the effects of 0, 21 and 42 mg transdermal nicotine on smoking, urge to smoke, and nicotine withdrawal symptoms after 5 hrs abstinence in smokers with schizophrenia and heavy-smoking non-psychiatric control smokers.
Interventions
- DRUG Transdermal Nicotine Patch
- DRUG placebo patch
- DRUG 21 mg transdermal nicotine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2002-06 |
| Est. Completion | 2005-02 |
| Phase | Phase 2 |
What the finished NCT00218218 record still lists
NCT00218218 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower).
The record links to 0 conditions, and to 3 interventions - of which Transdermal Nicotine Patch is the first listed.
NCT00218218 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00218218 about?
NCT00218218 is a clinical study titled "Effects of Transdermal Nicotine on Smoking, Craving and Withdrawal in People With Schizophrenia". Individuals with schizophrenia are three times as likely to smoke cigarettes as individuals without schizophrenia. While a great deal of research has been focused on smoking cessation programs for healthy individuals, little attention has been directed towards developing an effective smoking cessati...
What is the current status of trial NCT00218218?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 48 participants. The study started on 2002-06. Estimated completion is 2005-02.
What interventions are being tested in trial NCT00218218?
The interventions under investigation include: Transdermal Nicotine Patch (DRUG), placebo patch (DRUG), 21 mg transdermal nicotine (DRUG).
Who is sponsoring clinical trial NCT00218218?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00218218's enrollment target sits among peer trials
48 1265th of 2000 higher than 718 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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