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NCT00142727 · ClinicalTrials.gov registry record · Phase 2
Opioid Agonist and Antagonist Effects on Opioid Dependence
A Phase 2 study, sponsored by National Institute on Drug Abuse (NIDA).
- Terminated
- Registry status
- Phase 2
- Development phase
- 16
- Enrollment target
NCT00142727: Clinical Trial Phase 2 study, sponsored by National Institute on Drug Abuse (NIDA).
NCT00142727 is a Phase 2 study that was terminated before completion, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 16 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00142727, a Phase 2 study, was terminated before completion, sponsored by National Institute on Drug Abuse (NIDA).
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 16 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the acute agonist and antagonist effects of a full opioid agonist medication, an opioid antagonist medication, and a partial opioid agonist medication in individuals who have different levels of physical opioid dependence.
Interventions
- DRUG Methadone
- DRUG Full opioid agonist
- DRUG Partial opioid agonist
- DRUG Opioid antagonist
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2004-01 |
| Est. Completion | 2006-02 |
| Phase | Phase 2 |
Why NCT00142727 stopped before completion
NCT00142727 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 4 interventions - of which Methadone is the first listed.
NCT00142727 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00142727 about?
NCT00142727 is a clinical study titled "Opioid Agonist and Antagonist Effects on Opioid Dependence". The purpose of this study is to examine the acute agonist and antagonist effects of a full opioid agonist medication, an opioid antagonist medication, and a partial opioid agonist medication in individuals who have different levels of physical opioid dependence.
What is the current status of trial NCT00142727?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2004-01. Estimated completion is 2006-02.
What interventions are being tested in trial NCT00142727?
The interventions under investigation include: Methadone (DRUG), Full opioid agonist (DRUG), Partial opioid agonist (DRUG), Opioid antagonist (DRUG).
Who is sponsoring clinical trial NCT00142727?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00142727's enrollment target sits among peer trials
16 1908th of 2000 higher than 82 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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