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NCT00129272 · ClinicalTrials.gov registry record · Phase 2

Effectiveness of Bupropion for Treating Nicotine Dependence in Young People

A Phase 2 study of Tobacco Use Disorder and Tobacco Use Cessation, sponsored by National Institute on Drug Abuse (NIDA).

Completed
Registry status
Phase 2
Development phase
172
Enrollment target
1
Study location

NCT00129272 is a Phase 2 study of Tobacco Use Disorder and Tobacco Use Cessation that has completed, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 172 participants, below the 237-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (27% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00129272, a Phase 2 study of Tobacco Use Disorder and Tobacco Use Cessation, has completed, sponsored by National Institute on Drug Abuse (NIDA).

COMPLETED
Registry status
Phase 2
Development phase
172 participants
Enrollment target
1
Study location

Study Summary

Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers. The purpose of this study is to determine if bupropion is also effective in treating smokers between the ages of 12 and 25 years old. This study also compares the effectiveness of bupropion used as a supplement to behavioral treatment versus behavioral treatment used alone. In addition, the study evaluates whether hormonal response to stress measured prior to the start of treatment predicts whether individuals respond well to treatment with medication.

Interventions

  • OTHER Placebo
  • DRUG Bupropion-SR

Study Locations (1)

Texas

  • University of Texas Southwestern Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 172 participants
Start Date 2004-05
Est. Completion 2011-01
Phase Phase 2

What the Registry Record Tells You About NCT00129272

The ClinicalTrials.gov registry entry for NCT00129272 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 172 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 237-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (27% lower). The listed sponsor is National Institute on Drug Abuse (NIDA), which has 335 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Tobacco Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00129272 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT00129272 about?

NCT00129272 is a clinical study titled "Effectiveness of Bupropion for Treating Nicotine Dependence in Young People". Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers. The purpose of this study is to determine if bupropion is also effective in treating smokers between the ages of 12 and 25 yea...

What is the current status of trial NCT00129272?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2004-05. Estimated completion is 2011-01.

What conditions does trial NCT00129272 study?

This clinical trial studies the following conditions: Tobacco Use Disorder, Tobacco Use Cessation.

What interventions are being tested in trial NCT00129272?

The interventions under investigation include: Placebo (OTHER), Bupropion-SR (DRUG).

Who is sponsoring clinical trial NCT00129272?

This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00129272 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.