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NCT00129272 · ClinicalTrials.gov registry record · Phase 2
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
A Phase 2 study of Tobacco Use Disorder and Tobacco Use Cessation, sponsored by National Institute on Drug Abuse (NIDA).
- Completed
- Registry status
- Phase 2
- Development phase
- 172
- Enrollment target
- 1
- Study location
NCT00129272: Completed Phase 2 study of Tobacco Use Disorder and Tobacco Use Cessation, sponsored by National Institute on Drug Abuse (NIDA).
NCT00129272 is a Phase 2 study of Tobacco Use Disorder and Tobacco Use Cessation that has completed, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 172 participants, below the 237-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (27% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00129272, a Phase 2 study of Tobacco Use Disorder and Tobacco Use Cessation, has completed, sponsored by National Institute on Drug Abuse (NIDA).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 172 participants
- Enrollment target
- 1
- Study location
Study Summary
Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers. The purpose of this study is to determine if bupropion is also effective in treating smokers between the ages of 12 and 25 years old. This study also compares the effectiveness of bupropion used as a supplement to behavioral treatment versus behavioral treatment used alone. In addition, the study evaluates whether hormonal response to stress measured prior to the start of treatment predicts whether individuals respond well to treatment with medication.
Primary Outcome
Number of cigarettes smoked daily in the previous week
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Bupropion-SR
Study Locations (1)
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 172 participants |
| Start Date | 2004-05 |
| Est. Completion | 2011-01 |
| Phase | Phase 2 |
What the finished NCT00129272 record still lists
NCT00129272 is an interventional study that assigns participants to a tested intervention. The registered 172 participants enrollment target is mid-sized for trials with a published cap, below the 237-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (27% lower).
The record links to 2 conditions, with Tobacco Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00129272 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00129272 about?
NCT00129272 is a clinical study titled "Effectiveness of Bupropion for Treating Nicotine Dependence in Young People". Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers. The purpose of this study is to determine if bupropion is also effective in treating smokers between the ages of 12 and 25 yea...
What is the current status of trial NCT00129272?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2004-05. Estimated completion is 2011-01.
What conditions does trial NCT00129272 study?
This clinical trial studies the following conditions: Tobacco Use Disorder, Tobacco Use Cessation.
What interventions are being tested in trial NCT00129272?
The interventions under investigation include: Placebo (OTHER), Bupropion-SR (DRUG).
Who is sponsoring clinical trial NCT00129272?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00129272 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00129272's enrollment target sits among peer trials
172 25th of 70 higher than 46 of 70 other Tobacco Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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