National Institute on Drug Abuse (NIDA)
National Institute on Drug Abuse (NIDA) sponsors 335 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 292 completed. 30 of these trials are in Phase 3-4 (later-stage) and 202 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cocaine-Related Disorders, with 17 trials.
Trial Pipeline
335 total, page 5 of 7
Comparing the Effects of Smoked and Oral Marijuana in Individuals With HIV/AIDS
NCT00079560
Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens
NCT00218127
Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine
NCT00218166
Using Smokeless Tobacco Products With Lower Nicotine Levels to Reduce Negative Effects of Smokeless Tobacco Use
NCT00218244
Nicotine Patch for Nicotine Dependence in Individuals With Schizophrenia or Schizoaffective Disorder - 1
NCT00046813
Reserpine for the Treatment of Cocaine Dependence - 1
NCT00033033
A Study of Cabergoline for the Treatment of Cocaine Dependence - 1
NCT00033111
Evaluation of Benztropine for Cocaine Craving - 2
NCT00000333
Ondansetron for the Treatment of Cocaine Dependence - 1
NCT00033085
Randomized Trial of the Positive Action Program in Hawaii Schools
NCT00328445
Serotonin, Impulsivity, and Cocaine Dependence Treatment
NCT00297505
Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts
NCT00142779
Lofexidine for Opiate Withdrawal - 1
NCT00032942
Integrated Treatment for Cocaine and Mood Disorders - 1
NCT00227812
Selegiline Transdermal System for the Treatment of Cocaine Dependence - 1
NCT00032929
Substance Dependent Teens - Impact of Treating Depression Study 1 - 1
NCT00061113
Reduction of Smoking in Cardiac Disease Patients
NCT00469885
Physiological, Cognitive and Cerebral Activity Changes as a Function of Cigarette Smoking (With or Without Nicotine) and Tobacco Abstinence
NCT01034384
Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence
NCT00134888
Naltrexone Augmentation of Nicotine Patch Therapy - 1
NCT00218153
Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2
NCT00218010
Examining the Role of Negative Emotional States on Sedative Drug Use in Individuals With Post-Traumatic Stress Disorder
NCT00244335
Effectiveness of Nefazodone and Bupropion in Treating Marijuana Dependent Individuals
NCT00249509
Medication Adherence Therapy for Opioid Abusing Pain Patients
NCT00249587
Effectiveness of Divalproex Sodium (Depakote) in Treating Children With Temper Outbursts and Severe Mood Swings
NCT00217932
Maintenance Treatment for Abstinent Smokers
NCT00063323
Chemical Dependency and Smoking Cessation: Patient's Views - 1
NCT00051883
Student Athlete Testing Using Random Notification
NCT00451854
Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14
NCT00015340
Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence
NCT01208935
Progesterone Treatment in Female Smokers - 12
NCT00000295
Bupropion as an Adjunct to the Nicotine Patch Plus CBT
NCT00142831
Tiagabine, Sertraline, or Donepezil for the Treatment of Cocaine Dependence - 9
NCT00015132
Effect of Nefazodone on Relapse in Females With Cocaine Abuse - 10
NCT00000293
Motivation and Patch Treatment for HIV-positive Smokers
NCT00551720
Effects of Labetalol on Nicotine Administration in Humans - 14
NCT00000297
Effects of Carvedilol on Cocaine Use in Humans - 11
NCT00000294
Methylphendidate Treatment of Cocaine Dependent Patients With Attention Deficit Hyperactivity Disorder - 3
NCT00015054
Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke
NCT00307203
PET Assays of Striatal Dopamine Marker in Cocaine Craving
NCT01036516
High Dose Nimodipine Treatment Adjunct - 1
NCT00000332
Role of Metabolites in Nicotine Dependence (3) - 6
NCT00000289
Cocaine-Methylphendidate Interaction Study - 4
NCT00015067
Role of Metabolites in Nicotine Dependence (4) - 13
NCT00000296
Resperine, Gabapentin, or Lamotrigine for the Treatment of Cocaine Dependence: 2 - 7
NCT00015106
Effects of Labetalol on Human Cocaine Use - 8
NCT00000291
Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution - 1
NCT00000320
Temporal Discounting Delayed Outcomes on Opioid-Dependent Outpatients - 20
NCT00000238
Dextroamphetamine as an Adjunct in Cocaine Treatment - 1
NCT00000304
Risperidone for Treatment of Cocaine Dependence in Outpatients - 12
NCT00000347
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 81 |
| Phase 2 | 121 |
| Phase 3 | 14 |
| Phase 4 | 16 |
What the Pipeline for National Institute on Drug Abuse (NIDA) Shows
According to the ClinicalTrials.gov registry, National Institute on Drug Abuse (NIDA) is linked to 335 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 292 are already marked complete, representing roughly 87% of the total.
The phase mix for National Institute on Drug Abuse (NIDA) reports 30 late-stage studies (Phase 3 and Phase 4 combined) and 202 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute on Drug Abuse (NIDA) is Cocaine-Related Disorders with 17 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.