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NCT01036230 · ClinicalTrials.gov registry record
The Effects of Expectation on Natural and Drug -Induced Rewards
A clinical trial, sponsored by National Institute on Drug Abuse (NIDA).
- Completed
- Registry status
- 48
- Enrollment target
NCT01036230 is a clinical trial that has completed, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 48 participants.
The verdict
NCT01036230 has completed, sponsored by National Institute on Drug Abuse (NIDA).
- COMPLETED
- Registry status
- 48 participants
- Enrollment target
Study Summary
Background: * Environmental cues frequently induce expectancies in individuals that may strongly influence the actual experience associated with the cue. This has both positive and negative consequences for behavior and decision making. For instance, when an addicted individual experiences cues associated with imminent drug taking, an expectancy of the coming experience is also formed and very likely has an effect on the subsequent experience of the drug. * Researchers are interested in studying how the brain responds to these kinds of environmental cues and expectancies in order to learn more about addiction and craving in substance-abusing individuals. Objectives: * To compare the response to rewards (both drug-related and non-drug-related) in cocaine users and non-using individuals. * To study the effect of expectation on reward-related (both drug-induced and non-drug-induced) responses and brain activity in cocaine users and non-using individuals. Eligibility: -Individuals between 18 and 45 years of age who are regular cocaine users but otherwise healthy, or healthy individuals who are not cocaine users. Design: * This study involves two experiments. Participants will be assigned to one or both experiments. * Participants must not use any drugs for at least 3 days before the visit, may not consume alcohol for 24 hours before the visit, and may not consume caffeinated beverages for 12 hours before the visit. On the day of the visit, participants will provide both urine and breath samples to test for drug/alcohol use. * Experiment 1: In the MRI scanner, participants will respond to questions and images on a screen, and will receive small amounts of flavored liquid (chocolate or cherry) through a tube in the mouth. * Experiment 2: In the MRI scanner, participants will respond to questions and images on a screen, and will receive injections of liquid (saline solution or a drug that provides a high similar to cocaine) through an intravenous line. Participants
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2010-05-24 |
| Est. Completion | 2019-02-25 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01036230
The ClinicalTrials.gov registry entry for NCT01036230 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute on Drug Abuse (NIDA), which has 335 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01036230 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01036230 about?
NCT01036230 is a clinical study titled "The Effects of Expectation on Natural and Drug -Induced Rewards". Background: * Environmental cues frequently induce expectancies in individuals that may strongly influence the actual experience associated with the cue. This has both positive and negative consequences for behavior and decision making. For instance, when an addicted individual experiences cues ass...
What is the current status of trial NCT01036230?
This trial is currently completed. The enrollment target is 48 participants. The study started on 2010-05-24. Estimated completion is 2019-02-25.
Who is sponsoring clinical trial NCT01036230?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
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