Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00687713 · ClinicalTrials.gov registry record · Phase 2

Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence

A Phase 2 study, sponsored by National Institute on Drug Abuse (NIDA).

Completed
Registry status
Phase 2
Development phase
200
Enrollment target

NCT00687713: Completed Phase 2 study, sponsored by National Institute on Drug Abuse (NIDA).

NCT00687713 is a Phase 2 study that has completed, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 200 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00687713, a Phase 2 study, has completed, sponsored by National Institute on Drug Abuse (NIDA).

COMPLETED
Registry status
Phase 2
Development phase
200 participants
Enrollment target

Study Summary

This study is to assess the efficacy of bupropion in reducing methamphetamine use in subjects with methamphetamine dependence who report using methamphetamine 29 or less days during the 30 days prior to the start of signing consent.

Primary Outcome

The primary efficacy outcome measure was a measurement of treatment success or failure, where a subject who successfully achieved two weeks of abstinence during the last two weeks of investigational product dosing (Weeks 11 and 12) was scored as a success.

Interventions

  • OTHER Placebo
  • DRUG Bupropion

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2008-05
Est. Completion 2011-05
Phase Phase 2

What the finished NCT00687713 record still lists

NCT00687713 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00687713 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00687713 about?

NCT00687713 is a clinical study titled "Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence". This study is to assess the efficacy of bupropion in reducing methamphetamine use in subjects with methamphetamine dependence who report using methamphetamine 29 or less days during the 30 days prior to the start of signing consent.

What is the current status of trial NCT00687713?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2008-05. Estimated completion is 2011-05.

What interventions are being tested in trial NCT00687713?

The interventions under investigation include: Placebo (OTHER), Bupropion (DRUG).

Who is sponsoring clinical trial NCT00687713?

This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00687713's enrollment target sits among peer trials

200 304th of 2000 higher than 1,652 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00107289 · 200 participants · Phase 2

    Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

  • NCT00109174 · 200 participants · NA

    MRS Measurement of Glutamate and GABA Metabolism in Brain

  • NCT00177268 · 200 participants

    Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

  • NCT00493688 · 200 participants

    A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00687713, the US trial registry maintained by the National Library of Medicine. NCT00687713 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.