National Institute of Neurological Disorders and Stroke (NINDS)

567 total trials 48 currently recruiting 467 completed

National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.

Trial Pipeline

567 total, page 4 of 12

TERMINATED

Genetics of Motor Learning

NCT01105845

COMPLETED

The Influence of Sensory Stimuli on Gait Imagery in Patients With Freezing of Gait

NCT01071590

COMPLETED

Screening Protocol for Patients With Stroke

NCT01021033

COMPLETED NA

Physiological Investigations of Movement Disorders

NCT01019343

COMPLETED

Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study.

NCT01037361

TERMINATED

Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: a MEG Study

NCT01006109

COMPLETED Phase 1

50 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Parkinson's Disease

NCT00977184

COMPLETED Phase 1

High-Density Direct Current Brain Polarization

NCT00944931

COMPLETED Phase 1

A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm

NCT00942851

COMPLETED

GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression

NCT00931619

COMPLETED

Biomarkers of Risk of Parkinson Disease

NCT00775853

COMPLETED

Changes in the Posterior Parietal Cortex - Primary Motor Cortex Pathway Induced by Motor Training

NCT00904332

TERMINATED

Investigation of Neurofeedback With Real-Time fMRI in Healthy Volunteers and Patients With Hyperkinetic Movement Disorders

NCT00885040

COMPLETED

Effect of Reward on Learning in Motor Cortex

NCT00885131

COMPLETED

Magnetoencephalography in Absence Seizures

NCT00884351

TERMINATED Phase 1

An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma

NCT00880061

COMPLETED

Exploring a Motor Learning Technique Based on the Mirror Motor Neuron System

NCT00872183

COMPLETED Phase 1

Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor

NCT00848172

COMPLETED NA

Using Transcranial Direct Current Stimulation (tDCS) to Enhance the Benefit of Movement Training in Stoke Patients

NCT00783913

COMPLETED

Role of the Sensory Experience in Generating Motor Tics in Tourette Syndrome

NCT00755339

TERMINATED

Warfighter Head Injury Study

NCT00754169

COMPLETED

Brain Activity During Strategic Planning

NCT00728741

COMPLETED

Brain Activity in Time Discrimination and Sensory Input

NCT00726050

COMPLETED

Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia

NCT00713414

COMPLETED

Language Mapping in Patients With Epilepsy

NCT00706160

COMPLETED

Autoimmunity in Neurologic Complications of Celiac Disease

NCT00692861

COMPLETED Phase 1

Lithium Treatment for Patients With Spinocerebellar Ataxia Type I

NCT00683943

COMPLETED

Aneurysms and Carotid Artery Block in Newborns

NCT00646672

TERMINATED

Relationship of HHV-6B Virus to Seizures and Brain Injury

NCT00597285

COMPLETED

Association Between Focal Dystonia and Complex Regional Pain Syndrome

NCT00595439

COMPLETED

Motor Cortex Reward Signaling in Parkinson Disease

NCT00558766

COMPLETED Early Phase 1

Neurobiology of Functional Movement Disorder and Non-Epileptic Seizures

NCT00500994

TERMINATED Phase 1

Augmenting Effects of L-DOPS With Carbidopa and Entacapone

NCT00547911

COMPLETED

Brain Changes in Blepharospasm

NCT00500799

COMPLETED

Brain Function in Performance of Motor Tasks

NCT00498329

TERMINATED

Brain Changes in Blepharospasm

NCT00487383

COMPLETED

Movement of Epiglottis During Swallowing

NCT00475943

COMPLETED

Influence of Area of Brain Damage on Brain Reorganization After Chronic Stroke

NCT00474292

COMPLETED Phase 1

Botulinum Toxin to Treat Restless Legs Syndrome

NCT00479154

COMPLETED Phase 1

Effect of Electrical Stimulation (DC Polarization) to the Brain on Memory

NCT00471107

COMPLETED

Measuring Blood Flow in the Brain

NCT00466934

TERMINATED

Characteristics of Parkinson s Disease Associated With the LRRK-2 Gene Mutation

NCT00467090

COMPLETED

A Study to Evaluate and Characterize the Effect of Pharmacological Chemicals on Blood From Patients With Gaucher Disease

NCT00465062

COMPLETED

Brain Activity in People With Functional Movement Disorders

NCT00448084

TERMINATED

The Role of Serotonin in Seizures

NCT00439387

COMPLETED Phase 1

Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis

NCT00432900

COMPLETED

Sequence Effect in Parkinson's Disease

NCT00431366

COMPLETED

Spaced Versus Massed Skill Learning

NCT00426465

COMPLETED Early Phase 1

Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System

NCT00453505

COMPLETED Phase 1

Direct Current Brain Polarization of the Frontal Lobes

NCT00424216

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 78
Phase 3 11
Phase 4 5

What the Pipeline for National Institute of Neurological Disorders and Stroke (NINDS) Shows

According to the ClinicalTrials.gov registry, National Institute of Neurological Disorders and Stroke (NINDS) is linked to 567 US clinical trials across every stage of research activity. Of those, 48 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 467 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Neurological Disorders and Stroke (NINDS) reports 16 late-stage studies (Phase 3 and Phase 4 combined) and 158 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Neurological Disorders and Stroke (NINDS) is Healthy with 23 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.