National Institute of Neurological Disorders and Stroke (NINDS)

567 total trials 48 currently recruiting 467 completed

National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.

Trial Pipeline

567 total, page 3 of 12

COMPLETED Phase 1

Botulinum Toxin for Pelvic Pain in Women With Endometriosis

NCT01553201

COMPLETED Phase 2

Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia

NCT02199509

TERMINATED

Clinical Autonomic Disorders: A Training Protocol

NCT02154009

COMPLETED Phase 1

Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only)

NCT02108002

COMPLETED Phase 2

Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency

NCT02019667

TERMINATED

fMRI Neurofeedback for Motor Rehabilitation

NCT02089776

TERMINATED

Depotentiation in People With Focal Hand Dystonia

NCT02106936

COMPLETED Phase 1

Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp

NCT02015039

COMPLETED

Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions

NCT01974427

COMPLETED Phase 1

Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People With Multiple Sclerosis

NCT01326715

COMPLETED

Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation

NCT01925196

COMPLETED Early Phase 1

Raltegravir for HAM/TSP

NCT01867320

TERMINATED Phase 1

Effects of Exercise on Memory in Healthy and Brain-Injured Individuals

NCT01939769

TERMINATED

Cerebrospinal Fluid Collection and Repository Storage

NCT01862107

COMPLETED

The Effects of Repetitive Paired Associative Stimulation in Dystonia

NCT01888926

TERMINATED

A Study of Movement Disorders Using the QMAT At-Home Testing Device

NCT01905839

COMPLETED Early Phase 1

Exercise Education for Adults With Seizure Disorders

NCT01856335

COMPLETED

Imaging Studies of Cognitive Impairment in Parkinson s Disease

NCT01862744

TERMINATED

Natural History of Optic Neuritis

NCT01851434

COMPLETED Phase 1

AAV2-GDNF for Advanced Parkinson s Disease

NCT01621581

TERMINATED

Transcranial Magnetic Stimulation for Focal Hand Dystonia

NCT01792336

COMPLETED NA

Treatment of Functional Movement Disorders With Psychotherapy

NCT01778517

COMPLETED NA

Effects of Transcranial Magnetic Stimulation on Object Recognition

NCT01747200

TERMINATED Phase 2

Acetyl Hexapeptide-8 for Blepharospasm

NCT01750346

COMPLETED

Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility

NCT01617395

COMPLETED

Brain P-gp and Inflammation in People With Epilepsy

NCT01663545

COMPLETED

The Effects of Chronic Exposure to Low-Level Blasts

NCT01524822

COMPLETED

Taurine Therapy for SSADH Deficiency

NCT01608178

COMPLETED

Validating a New Writer s Cramp Scale

NCT01579266

TERMINATED

Infants With Spinal Muscular Atrophy Type I

NCT01547871

COMPLETED

Studying Motor Neuron Tests

NCT01517087

COMPLETED

Imaging Biomarkers in Parkinson s Disease

NCT01496599

COMPLETED

Service Member Fatigue and Lack of Motivation Following Concussion

NCT01496586

TERMINATED Phase 2

Buspirone Therapy for Localized Epilepsy

NCT01496612

COMPLETED Phase 1

Octanoic Acid for Essential Tremor

NCT01468948

COMPLETED Early Phase 1

Effects of Hormone Stimulation on Brain Scans for Cushing s Disease

NCT01459237

COMPLETED

Studying Skeletal Muscle, Heart, and Diaphragm Imaging in Boys With Duchenne Muscular Dystrophy

NCT01451281

COMPLETED Phase 1

Effect of Functional Exercise in Patients With Spinal Bulbar Muscular Atrophy

NCT01369901

TERMINATED

Brain Areas Involved in Sound and Spoken Word Memory

NCT01375595

COMPLETED

Structural and Functional Neuroimaging Studies of Combat Veterans

NCT01296126

TERMINATED Phase 2

PRX-00023 Therapy in Localization-Related Epilepsy

NCT01281956

COMPLETED Phase 1

Intravenous Norepinephrine for Orthostatic Hypotension

NCT01285908

TERMINATED

The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans

NCT01260740

COMPLETED

Evaluation, Pathogenesis, and Outcome of Subjects With or Suspected Traumatic Brain Injury

NCT01132937

COMPLETED

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

NCT01222728

TERMINATED Phase 1

Double Blind Combination of Rituximab by Intravenous and Intrathecal Injection Versus Placebo in Patients With Low-Inflammatory Secondary Progressive Multiple Sclerosis (RIVITaLISe)

NCT01212094

COMPLETED

Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates

NCT01200966

COMPLETED

Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

NCT01194661

COMPLETED

Oxidative Stress in Motor Neuron Disease: COSMOS Add-On Study

NCT01143428

COMPLETED Phase 1

Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS)

NCT01143441

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 78
Phase 3 11
Phase 4 5

What the Pipeline for National Institute of Neurological Disorders and Stroke (NINDS) Shows

According to the ClinicalTrials.gov registry, National Institute of Neurological Disorders and Stroke (NINDS) is linked to 567 US clinical trials across every stage of research activity. Of those, 48 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 467 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Neurological Disorders and Stroke (NINDS) reports 16 late-stage studies (Phase 3 and Phase 4 combined) and 158 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Neurological Disorders and Stroke (NINDS) is Healthy with 23 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.