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NCT00500994 · ClinicalTrials.gov registry record · Early Phase 1
Neurobiology of Functional Movement Disorder and Non-Epileptic Seizures
A Early Phase 1 study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- Early Phase 1
- Development phase
- 254
- Enrollment target
NCT00500994: Completed Early Phase 1 study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00500994 is a Early Phase 1 study that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 254 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (379% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00500994, a Early Phase 1 study, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 254 participants
- Enrollment target
Study Summary
This study is part of a series of studies that will explore how the mind and the brain work to cause episodes of uncontrollable shaking in people who have no known underlying brain or medical disorder. The study is conducted at NIH and at the Brown University Rhode Island Hospital. Healthy volunteers and people with functional movement disorders (FMD) or non-epileptic seizures (NES) who are 18 years of age or older may be eligible for this study. Patients with NES have 3 teaspoons of blood drawn. The blood is tested for two genes that are normally found in healthy individuals to see if they are found more frequently in patients with uncontrolled shaking. Patients with FMD have blood drawn for testing and also undergo functional magnetic resonance imaging (fMRI) to look at how the brain functions while the subject performs a specific task. MRI uses a strong magnetic field and radio waves to obtain images of body organs and tissues. During the scan, the subject lies on a table that can slide in and out of the scanner, a metal cylinder. The scan lasts about 60 to 90 minutes, during which the subject may be asked to lie still for up to 10 minutes at a time and to perform tasks, such as identifying the gender of faces shown on a screen. Healthy volunteers may have blood drawn for genetic testing or fMRI or both.
Primary Outcome
fMRI BOLD signal change focusing on regions of interest during emotional valence task
Interventions
- DEVICE MRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 254 participants |
| Start Date | 2007-10-05 |
| Est. Completion | 2022-12-13 |
| Phase | Early Phase 1 |
What the finished NCT00500994 record still lists
NCT00500994 is an interventional study that assigns participants to a tested intervention. The registered 254 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (379% higher).
The record links to 0 conditions, and to 1 intervention - of which MRI is the first listed.
NCT00500994 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00500994 about?
NCT00500994 is a clinical study titled "Neurobiology of Functional Movement Disorder and Non-Epileptic Seizures". This study is part of a series of studies that will explore how the mind and the brain work to cause episodes of uncontrollable shaking in people who have no known underlying brain or medical disorder. The study is conducted at NIH and at the Brown University Rhode Island Hospital. Healthy voluntee...
What is the current status of trial NCT00500994?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 254 participants. The study started on 2007-10-05. Estimated completion is 2022-12-13.
What interventions are being tested in trial NCT00500994?
The interventions under investigation include: MRI (DEVICE).
Who is sponsoring clinical trial NCT00500994?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00500994's enrollment target sits among peer trials
254 44th of 2000 higher than 1,957 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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