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NCT00426465 · ClinicalTrials.gov registry record
Spaced Versus Massed Skill Learning
A clinical trial of Healthy Volunteer, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 213
- Enrollment target
- 1
- Study location
NCT00426465: Completed study of Healthy Volunteer, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00426465 is a study of Healthy Volunteer that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 213 participants, roughly in line with the 200-participant average among 112 other Healthy Volunteer trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00426465, a study of Healthy Volunteer, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 213 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will explore the optimum training schedule for stroke patients to learn motor skills. It will see if motor training is more effective when training sessions are distributed over time (spaced training) or when the sessions are scheduled close together (massed training). The results of this study may help researchers devise the best training schedule for patients to derive the maximum benefit from rehabilitation therapy. Healthy normal volunteers and people who have had a stroke may be eligible for this study. Patients must be 3 months post-stroke. All participants must be right-handed and between 18 and 80 years of age. Participants practice a pinch motor task and receive transcranial magnetic stimulation (TMS). Hand muscle activity is measured using surface electromyography (EMG). Pinch training involves training the participant to pinch as strongly as possible, using a device that records the force. For TMS, a wire coil is held on the subject s scalp. A brief electrical current is passed through the coil, creating a magnetic pulse that stimulates the brain. The subject hears a click and may feel a pulling sensation on the skin under the coil. There may be a twitch in the muscles of the face, arm or leg. For surface EMG, electrodes (small metal disks) are filled with a conductive gel and taped to the skin over the muscle. Following one practice session of pinch task training and TMS, participants have four training sessions, which are scheduled 24 hours, 2 weeks, 1 month and 3 months after the practice session. For the 4- to 5-hour practice session, subjects do the following: * Perform a single session of pinch motor task for familiarization * Undergo TMS to measure brain activity * Practice five 6-minute blocks of pinch motor task with rest periods between sessions and perform a calculation task (addition and subtraction tasks) during each rest period * Receive TMS over 15 minutes. (Some sessions may have sham TMS.) * Read books and magazines during
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 213 participants |
| Start Date | 2007-01-17 |
| Est. Completion | 2013-12-16 |
What the finished NCT00426465 record still lists
NCT00426465 is an observational study that tracks outcomes without assigning an intervention. The registered 213 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 200-participant average among 112 other Healthy Volunteer trials with a reported enrollment target.
The record links to 1 condition, with Healthy Volunteer appearing as the primary indexed condition, and to 0 interventions.
NCT00426465 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00426465 about?
NCT00426465 is a clinical study titled "Spaced Versus Massed Skill Learning". This study will explore the optimum training schedule for stroke patients to learn motor skills. It will see if motor training is more effective when training sessions are distributed over time (spaced training) or when the sessions are scheduled close together (massed training). The results of this...
What is the current status of trial NCT00426465?
This trial is currently completed. The enrollment target is 213 participants. The study started on 2007-01-17. Estimated completion is 2013-12-16.
What conditions does trial NCT00426465 study?
This clinical trial studies the following conditions: Healthy Volunteer.
Who is sponsoring clinical trial NCT00426465?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00426465 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00426465's enrollment target sits among peer trials
213 14th of 112 higher than 99 of 112 other Healthy Volunteer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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