National Institute of Neurological Disorders and Stroke (NINDS)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Neurological Disorders and Stroke (NINDS) sits in the top decile of US sponsors by registered trial count (#61 of 15,742 sponsors by registered trial count).

567 total trials 48 currently recruiting 467 completed early-phase tilt top decile by trial count

National Institute of Neurological Disorders and Stroke (NINDS): 567 sponsored US clinical trials, 48 recruiting.

National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.

Top-decile sponsor footprint

National Institute of Neurological Disorders and Stroke (NINDS) ranks in the top decile of sponsors by registered trial count (#61 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 70/100

467 of 508 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

567 total, page 5 of 12

COMPLETED

Detecting a Reward Signal in the Motor Cortex

NCT00422071

COMPLETED

MRI of Alzheimer's Disease Imaging Amyloid Plaques in Persons With and Without Memory Problems

NCT00413621

COMPLETED

Effects of tDCS Over the Cerebellum on Motor Function

NCT00413842

COMPLETED

Enhancing Brain Activity With Magnetic Stimulation

NCT00396890

COMPLETED

Motor Skill Learning in People With Parkinson's Disease

NCT00396942

COMPLETED

Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis

NCT00393588

COMPLETED

Enhancing Motor Task Training by Action Observation Watching Others Perform the Task

NCT00393432

COMPLETED

Brain Connectivity Between Visual Input and Movement

NCT00376545

COMPLETED

Muscle Contraction in Patients With Focal Hand Dystonia

NCT00376753

COMPLETED

Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)

NCT00391378

COMPLETED

Hypersensitivity in Tourette Syndrome

NCT00368433

COMPLETED

Influence of Theta Burst Stimulation and Carbidopa-Levodopa on Motor Performance in Stroke Patients

NCT00366184

COMPLETED

Collection of Blood Samples for DNA in Motor Neuron Disease

NCT00362362

COMPLETED

Plasma Exchange for Autoimmune Autonomic Failure

NCT00359346

COMPLETED Phase 2

A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia

NCT00376506

COMPLETED Phase 2

Brain Stimulation to Treat Blepharospasm or Meige Syndrome

NCT00411255

COMPLETED

Electrical Brain Stimulation to Reduce Epileptic Seizures

NCT00344877

COMPLETED

Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis

NCT00334516

COMPLETED

Gait Training and Brain Changes in Stroke Patients

NCT00334230

COMPLETED

Improving Hand Movement Training Through Electrical Stimulation of the Brain

NCT00331318

COMPLETED

Long-Term Motor Learning in Focal Hand Dystonia

NCT00325091

COMPLETED

Plasticity in Cervical Dystonia

NCT00323765

COMPLETED

Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis

NCT00321568

COMPLETED

Long-Term Improvement in Motor Learning by Transcranial Direct Current Stimulation

NCT00314769

COMPLETED

Treatment for Psychogenic Disorders

NCT00314444

COMPLETED

fMRI Studies of Task Specificity in Focal Hand Dystonia

NCT00310414

COMPLETED

Neurophysiology of Task-Specificity of Focal Hand Dystonia

NCT00309010

COMPLETED

Physiology of Weakness in Movement Disorders

NCT00307346

COMPLETED

Transcranial Direct Current Stimulation to Improve Hand Movement in Stroke Patients

NCT00307385

COMPLETED Phase 2

Volitional Swallowing in Stroke Patients With Chronic Dysphagia

NCT00306501

COMPLETED

Brain Changes in Patients With Focal Hand Dystonia

NCT00306865

COMPLETED Phase 1

Reference Values for Plasma Catechols

NCT00267904

COMPLETED Phase 2

Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA)

NCT00303446

COMPLETED

Interaction of Right and Left Brain Hemispheres in Learning Precision Hand Movements

NCT00295568

COMPLETED

Effect of Atorvastatin (Lipitor) on Gene Expression in People With Vascular Disease

NCT00293748

COMPLETED

Measures of Motor Impairment in Early Parkinson's Disease

NCT00291265

COMPLETED

Diffusion Tensor MRI to Distinguish Brain Tumor Recurrence From Radiation Necrosis

NCT00285324

COMPLETED

Brain Networks Responsible for Sense of Agency

NCT00283907

COMPLETED

Tactile Learning in Stroke Patients

NCT00283881

COMPLETED Phase 2

Electrical Polarization of the Brain in Corticobasal Syndrome

NCT00273897

COMPLETED

Brain Changes in Adolescents While Imagining and Observing Aggressive Behavior

NCT00267891

COMPLETED

Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure

NCT00255411

COMPLETED

Training for Diagnosing Neurological Disorders

NCT00132353

COMPLETED

Brain Networks Responsible for Self-Agency

NCT00246831

COMPLETED

PET Imaging of GABA Receptors in Succinic Semialdehyde Dehydrogenase Deficiency

NCT00246870

COMPLETED

Convection-Enhanced Delivery of Glucocerebrosidase to Treat Type 2 Gaucher Disease

NCT00244582

TERMINATED

Moving a Paralyzed Hand Through Use of a Brain-Computer Interface

NCT00242242

COMPLETED Phase 2

Idebenone to Treat Friedreich's Ataxia

NCT00229632

COMPLETED

Brain Activity Associated With Tics in Patients With Tourette Syndrome

NCT00141869

COMPLETED

Movement-Related Brain Networks Involved in Hand Dystonia

NCT00137384

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Phase Distribution

PhaseTrial count
Phase 1 80
Phase 2 78
Phase 3 11
Phase 4 5

What is open in the National Institute of Neurological Disorders and Stroke (NINDS) pipeline

48 recruiting of 567 indexed (8% open); 467 completed (82%).

Phase mix: 16 late (III/IV) vs 158 early (I/II) (early-phase heavy).

Top condition: Healthy (23 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Neurological Disorders and Stroke (NINDS): open-pipeline peers nationwide

Peers matched on 567 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Neurological Disorders and Stroke (NINDS) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share National Institute of Neurological Disorders and Stroke (NINDS)Children's Hospital Medical Center, CincinnatiUniversity of Maryland, BaltimoreAmgenMerck Sharp & DohmeNational Jewish HealthACADIA PharmaceuticalsTexas Tech University Health Sciences Center, El PasoBoehringer Ingelheim
National Institute of Neurological Disorders and Stroke (NINDS) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Neurological Disorders and Stroke (NINDS) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 567 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Neurological Disorders and Stroke (NINDS) page

567 registered trials is a research-attention snapshot, not an endorsement of National Institute of Neurological Disorders and Stroke (NINDS) or any single study.

  • 48 of National Institute of Neurological Disorders and Stroke (NINDS)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institute of Neurological Disorders and Stroke (NINDS) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Neurological Disorders and Stroke (NINDS) pipeline card: 567 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.