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NCT00726050 · ClinicalTrials.gov registry record
Brain Activity in Time Discrimination and Sensory Input
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 4
- Enrollment target
NCT00726050 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 4 participants.
The verdict
NCT00726050 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 4 participants
- Enrollment target
Study Summary
This study will use repetitive transcranial magnetic stimulation, or rTMS (magnetic stimulation to the brain), to examine how the brain distinguishes between two signals that are spaced very closely in time. The ability to tell the difference between sensory signals is important to understanding sensory input. Understanding how this works may help to develop new treatments for sensory deficits. Healthy volunteers 18 years of age and older may be eligible for this study. Participants undergo the following procedures during three visits to the NIH Clinical Center: rTMS - all visits (sham rTMS on one visit) : For TMS, a wire coil is held on the scalp. A brief electrical current passed through the coil creates a magnetic pulse that stimulates the brain. During the stimulation, the subject may be asked to tense certain muscles slightly or perform other simple actions. Theta burst stimulation (TBS) - all visits (sham TBS on one visit): Same as TMS, but brief pulses of electrical current are passed through the coil. Subjects undergo intermittent TBS on one visit and continuous TBS on another. Somatosensory evoked potential (SEP) - all visits: SEP tests how sensory information travels along the nerves to the spinal cord and brain. A small metal disk electrode placed on an arm delivers a small electrical shock. Electrodes placed on the scalp record how the impulse travels over the nerve pathways to the cerebral cortex of the brain. EEG (see below) records what sensory information the brain is detecting and processing. Paired-pulse SEP is done before and after TBS. Temporal discrimination threshold - all visits: This test investigates the brain's ability to discriminate sensory information. Electrodes are placed on the subject's wrist. Two electrical pulses are delivered to the nerve at the wrist at different spaced intervals to determine when the subject feels the two pulses are fused into one. This test is done before and after TBS. Electroencephalography (EEG) -
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2008-07-28 |
| Est. Completion | 2010-04-29 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00726050
The ClinicalTrials.gov registry entry for NCT00726050 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00726050 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00726050 about?
NCT00726050 is a clinical study titled "Brain Activity in Time Discrimination and Sensory Input". This study will use repetitive transcranial magnetic stimulation, or rTMS (magnetic stimulation to the brain), to examine how the brain distinguishes between two signals that are spaced very closely in time. The ability to tell the difference between sensory signals is important to understanding sen...
What is the current status of trial NCT00726050?
This trial is currently completed. The enrollment target is 4 participants. The study started on 2008-07-28. Estimated completion is 2010-04-29.
Who is sponsoring clinical trial NCT00726050?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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