National Institute of Mental Health (NIMH)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Mental Health (NIMH) sits in the top decile of US sponsors by registered trial count (#103 of 15,742 sponsors by registered trial count).

343 total trials 42 currently recruiting 256 completed early-phase tilt top decile by trial count

National Institute of Mental Health (NIMH): 343 sponsored US clinical trials, 42 recruiting.

National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.

Top-decile sponsor footprint

National Institute of Mental Health (NIMH) ranks in the top decile of sponsors by registered trial count (#103 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 56/100

256 of 296 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

343 total, page 7 of 7

COMPLETED

The Evaluation and Follow-up of Patients With Bipolar Disorder

NCT00001652

COMPLETED

Genetics of Obsessive-Compulsive Disorder

NCT00001548

COMPLETED

Neuropsychiatric Effects of Interferon-Alpha and Ribavirin

NCT00001547

COMPLETED

Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers

NCT00001546

COMPLETED Phase 2

Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders

NCT00001545

COMPLETED Phase 2

The Role of Hormones in Postpartum Mood Disorders

NCT00001481

COMPLETED

Genetic Aspects of Neurologic and Psychiatric Disorders

NCT00001544

COMPLETED

Dynamics of Leptin and Endocrine Function

NCT00001543

COMPLETED

Genetic Study of Schizophrenia

NCT00001486

COMPLETED

Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder

NCT00001485

COMPLETED Phase 2

Acute Effectiveness of Additional Drugs to the Standard Treatment of Depression

NCT00001483

COMPLETED Phase 2

Treatment of Mid-Life-Related Mood Disorders

NCT00001487

COMPLETED Phase 2

New Drugs in the Treatment of Mood Disorders

NCT00001482

COMPLETED

The Evaluation and Follow-up of Individuals With Memory Disorder

NCT00001480

COMPLETED

Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression

NCT00001479

COMPLETED

Effects of Drugs on Cerebral Blood Flow in Patients With Mood Disorders

NCT00001478

COMPLETED Phase 1

The Effects of Reproductive Hormones on Mood and Behavior

NCT00001322

COMPLETED

Glucocorticoid Effects on Cellular Cytokine Release

NCT00001415

COMPLETED

Bone Mineral Density in Women With Major Depression

NCT00001413

COMPLETED

Mapping Personality Traits to Genes

NCT00001414

COMPLETED

Effects on the Brain of Lupron Induced Hypogonadotropic Hypogonadism With and Without Testosterone Replacement

NCT00001412

COMPLETED

Studies of Frontal Lobe Brain Functioning in Schizophrenia

NCT00001258

COMPLETED Phase 1

PEG-Glucocerebrosidase for the Treatment of Gaucher Disease

NCT00001410

COMPLETED Phase 2

Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup)

NCT00001359

COMPLETED Phase 1

A Treatment Study for Premenstrual Syndrome (PMS)

NCT00001259

COMPLETED

Neuropsychiatric Evaluation of Healthy Volunteers and Adults With Schizophrenia

NCT00001323

COMPLETED

Models of Disordered Knowledge and Memory Systems in Dementia and Related Disorders

NCT00004557

COMPLETED

Neuroimaging of Dopamine Metabolism in Normal and Psychiatric Patients

NCT00001320

COMPLETED

The Effects of Dextroamphetamine on Brain Function

NCT00004556

COMPLETED

Effects of Sex Hormones on Circadian Rhythm in Men and Women

NCT00001285

COMPLETED

Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers

NCT00001284

TERMINATED

Brain Tissue Collection for Neuropathological Studies

NCT00001260

COMPLETED Phase 2

Phase II Study of the Efficacy of Peptide T in HIV-Positive Individuals With Cognitive Impairment.

NCT00000392

COMPLETED

Inpatient Evaluation of Adults With Schizophrenia

NCT00001247

COMPLETED

Perimenopause-Related Mood and Behavioral Disorders

NCT00001231

COMPLETED

Study of Children at Risk for Disruptive Behavior Disorders

NCT00001233

COMPLETED

The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders

NCT00001232

COMPLETED Phase 1

A Phase I Trial of Peptide T: Efficacy for the Neuropsychiatric Complications of Acquired Immunodeficiency Syndrome (AIDS).

NCT00000393

COMPLETED Phase 1

A Phase I Trial of Intranasal Peptide T: Safety, Toxicity, and Pharmacokinetics in Human Immunodeficiency Virus-1 (HIV-1) Infected Patients.

NCT00000391

COMPLETED

Biological Markers in Attention Deficit/Hyperactivity Disorder (ADHD)

NCT00001206

TERMINATED

Evaluating Genetic Risk Factors for Childhood-Onset Schizophrenia

NCT00001198

COMPLETED

Neuropsychological Evaluation of Psychiatric and Neurological Patients

NCT00001192

COMPLETED

Study of the Psychological Development of Children of Parents With and Without Affective Disorders

NCT00001170

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Phase Distribution

PhaseTrial count
Phase 1 61
Phase 2 45
Phase 3 8
Phase 4 21

What is open in the National Institute of Mental Health (NIMH) pipeline

42 recruiting of 343 indexed (12% open); 256 completed (75%).

Phase mix: 29 late (III/IV) vs 106 early (I/II) (early-phase heavy).

Top condition: Healthy (21 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Mental Health (NIMH): open-pipeline peers nationwide

Peers matched on 343 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

National Institute of Mental Health (NIMH) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400 5%10%15%20%25% Total trials Recruiting share National Institute of Mental Health (NIMH)Children's Oncology GroupMontefiore Medical CenterOhio State University Comprehensive Cancer CenterCedars-Sinai Medical CenterAugusta UniversityUniversity of IowaDaiichi SankyoFriends Research Institute
National Institute of Mental Health (NIMH) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Mental Health (NIMH) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 343 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this National Institute of Mental Health (NIMH) page

343 registered trials is a research-attention snapshot, not an endorsement of National Institute of Mental Health (NIMH) or any single study.

  • 42 of National Institute of Mental Health (NIMH)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institute of Mental Health (NIMH) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Mental Health (NIMH) pipeline card: 343 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.