Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00004556 · ClinicalTrials.gov registry record
The Effects of Dextroamphetamine on Brain Function
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 108
- Enrollment target
NCT00004556: Completed study, sponsored by National Institute of Mental Health (NIMH).
NCT00004556 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 108 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00004556 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 108 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effects of the drug dextroamphetamine on the brain function and mood of healthy volunteers. Monoaminergic drugs are substances that affect the nervous system; these drugs can raise, hamper, or have no effect on brain function when given to healthy individuals. Different responses to a drug may be the result of genetic variations. This study will examine the effects of the monoaminergic drug dextroamphetamine on thought and sensorimotor processes while participants perform a variety of tasks. Participants in this study will undergo a medical history, physical examination, blood tests, and an electrocardiogram (EKG). Women of reproductive potential will undergo a pregnancy test. Participants will be given either dextroamphetamine or placebo (an inactive solution) on two occasions separated by at least 3 to 7 days. Participants will then perform neuropsychological tests that will measure attention, problem solving, memory, and ability to complete simple motor tasks.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 1991-09-30 |
| Est. Completion | 2018-09-25 |
What the finished NCT00004556 record still lists
NCT00004556 is an observational study that tracks outcomes without assigning an intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00004556 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00004556 about?
NCT00004556 is a clinical study titled "The Effects of Dextroamphetamine on Brain Function". The purpose of this study is to determine the effects of the drug dextroamphetamine on the brain function and mood of healthy volunteers. Monoaminergic drugs are substances that affect the nervous system; these drugs can raise, hamper, or have no effect on brain function when given to healthy indiv...
What is the current status of trial NCT00004556?
This trial is currently completed. The enrollment target is 108 participants. The study started on 1991-09-30. Estimated completion is 2018-09-25.
Who is sponsoring clinical trial NCT00004556?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02703207 · 108 participants · NA
Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD
- NCT02744677 · 108 participants · NA
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
- NCT02781883 · 108 participants · Phase 2
Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
- NCT03848663 · 108 participants · NA
Visual Remapping to Aid Reading With Field Loss
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI