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NCT00001231 · ClinicalTrials.gov registry record
Perimenopause-Related Mood and Behavioral Disorders
A clinical trial of Mood Disorder, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 1,158
- Enrollment target
- 1
- Study location
NCT00001231 is a study of Mood Disorder that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 1,158 participants, roughly in line with the 1,142-participant average among 7 other Mood Disorder trials with a reported enrollment target. The trial reports 1 study location across 1 state.
The verdict
NCT00001231, a study of Mood Disorder, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 1,158 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate mood and behavior changes in the time period surrounding and including menopause. This is an observational study; volunteers who participate will not receive any new or experimental therapies. Controversy exists regarding the relationship between estrogen and progesterone (gonadal steroid) changes and midlife-onset depression. This study will examine the role of gonadal steroids in perimenopausal mood and behavioral disorders. Perimenopausal women with depression symptoms and a control group of healthy perimenopausal volunteers will be compared to identify correlates of the occurrence of depression. Participants with depressive symptoms may also participate in companion studies that will test the antidepressant efficacy of phytoestrogens and selective estrogen receptor modulators (SERMS). A group of younger pre-perimenopausal women with normal menstrual cycle functioning will be followed through menopause in an effort to confirm the association of depression onset with changes in reproductive endocrine functioning.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,158 participants |
| Start Date | 1989-03-06 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001231
The ClinicalTrials.gov registry entry for NCT00001231 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 1,158 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 1,142-participant average among 7 other Mood Disorder trials with a reported enrollment target. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Mood Disorder appearing as the primary indexed condition, and to 0 interventions.
NCT00001231 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00001231 about?
NCT00001231 is a clinical study titled "Perimenopause-Related Mood and Behavioral Disorders". The purpose of this study is to investigate mood and behavior changes in the time period surrounding and including menopause. This is an observational study; volunteers who participate will not receive any new or experimental therapies. Controversy exists regarding the relationship between estrogen...
What is the current status of trial NCT00001231?
This trial is currently completed. The enrollment target is 1,158 participants. The study started on 1989-03-06.
What conditions does trial NCT00001231 study?
This clinical trial studies the following conditions: Mood Disorder.
Who is sponsoring clinical trial NCT00001231?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001231 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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