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NCT00001478 · ClinicalTrials.gov registry record
Effects of Drugs on Cerebral Blood Flow in Patients With Mood Disorders
A clinical trial of Healthy and Mood Disorders, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 170
- Enrollment target
- 1
- Study location
NCT00001478: Completed study of Healthy and Mood Disorders, sponsored by National Institute of Mental Health (NIMH).
NCT00001478 is a study of Healthy and Mood Disorders that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 170 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001478, a study of Healthy and Mood Disorders, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 170 participants
- Enrollment target
- 1
- Study location
Study Summary
Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal biochemical and metabolic processes of the central nervous system of normal individuals and patients with neurologic illnesses without physical / structural damage to the brain. When a region of the brain is active, it uses more fuel in the form of oxygen and sugar (glucose). As the brain uses more fuel it produces more waste products, carbon dioxide and water. Blood carries fuel to the brain and waste products away from the brain. As brain activity increases blood flow to and from the area of activity increases also. Knowing these facts, researchers can use radioactive chemicals (H215O) and PET scans to observe what areas of the brain are receiving more blood flow. Patients diagnosed with mood disorders and healthy volunteers will receive positron emission tomographic (PET) scans with H215O while doing simple tasks. Patients will continue to receive scans while in different mood states and while taking different medications. Patients eligible for this study will be participating in other research studies measuring other clinical and biochemical parameters (mood and anxiety ratings, medication responses, and psychological test results). Information gathered from H215O PET scans measuring blood flow to specific brain areas will be compared to the data gathered from other studies. Objectives of this study are; 1. To determine differences in blood flow to the brain of patients with mood disorders compared to healthy volunteers. 2. To determine differences in blood flow to the brain of patients with subtype mood disorders (such as unipolar versus bipolar) compared to healthy volunteers. 2\. To determine changes in blood flow to the brain of patients with mood disorders who experience spontaneous changes in symptoms 3\. To determine changes in blood flow to the brain of patients with mood disorders who rece
Conditions Studied
Study Locations (1)
Maryland
- National Institute of Mental Health (NIMH) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 1994-10 |
| Est. Completion | 2001-01 |
What the finished NCT00001478 record still lists
NCT00001478 is an observational study that tracks outcomes without assigning an intervention. The registered 170 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (74% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 0 interventions.
NCT00001478 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001478 about?
NCT00001478 is a clinical study titled "Effects of Drugs on Cerebral Blood Flow in Patients With Mood Disorders". Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal biochemical and metabolic processes of the central nervous system of normal individuals and patients with neurologic illnesses without phys...
What is the current status of trial NCT00001478?
This trial is currently completed. The enrollment target is 170 participants. The study started on 1994-10. Estimated completion is 2001-01.
What conditions does trial NCT00001478 study?
This clinical trial studies the following conditions: Healthy, Mood Disorders.
Who is sponsoring clinical trial NCT00001478?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001478 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00001478's enrollment target sits among peer trials
170 141st of 1090 higher than 949 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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