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NCT00001920 · ClinicalTrials.gov registry record
Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 112
- Enrollment target
NCT00001920 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 112 participants.
The verdict
NCT00001920 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 112 participants
- Enrollment target
Study Summary
The purpose of this study is to explore how the brain works during particular memory tasks in people with schizophrenia and healthy volunteers. Research has shown that patients with schizophrenia have structural and functional abnormalities in the hippocampus and cerebellum of their brains. These abnormalities are likely associated with the memory impairment experienced by these patients. Eye blink tests can provide information about memory acquisition involving the cerebellar and hippocampal regions. By altering the stimuli interval, these tests can distinguish between cerebellum-dependent memory associated with subliminal mnemonic encoding and hippocampus-dependent memory associated with conscious awareness. This study will use eyeblink tests to determine which type of memory is predominantly affected in schizophrenia. Participants in this study will be screened with a physical and psychiatric examination. Participants will have an electroencephalogram (EEG), an electrocardiogram (ECG), and an electrodermal test. Evoked potentials and magnetic resonance imaging (MRI) scans of the brain may also be taken.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 1999-08-30 |
| Est. Completion | 2010-06-02 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001920
The ClinicalTrials.gov registry entry for NCT00001920 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 112 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00001920 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00001920 about?
NCT00001920 is a clinical study titled "Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia". The purpose of this study is to explore how the brain works during particular memory tasks in people with schizophrenia and healthy volunteers. Research has shown that patients with schizophrenia have structural and functional abnormalities in the hippocampus and cerebellum of their brains. These a...
What is the current status of trial NCT00001920?
This trial is currently completed. The enrollment target is 112 participants. The study started on 1999-08-30. Estimated completion is 2010-06-02.
Who is sponsoring clinical trial NCT00001920?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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