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NCT00001920 · ClinicalTrials.gov registry record
Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 112
- Enrollment target
NCT00001920: Completed study, sponsored by National Institute of Mental Health (NIMH).
NCT00001920 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 112 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001920 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 112 participants
- Enrollment target
Study Summary
The purpose of this study is to explore how the brain works during particular memory tasks in people with schizophrenia and healthy volunteers. Research has shown that patients with schizophrenia have structural and functional abnormalities in the hippocampus and cerebellum of their brains. These abnormalities are likely associated with the memory impairment experienced by these patients. Eye blink tests can provide information about memory acquisition involving the cerebellar and hippocampal regions. By altering the stimuli interval, these tests can distinguish between cerebellum-dependent memory associated with subliminal mnemonic encoding and hippocampus-dependent memory associated with conscious awareness. This study will use eyeblink tests to determine which type of memory is predominantly affected in schizophrenia. Participants in this study will be screened with a physical and psychiatric examination. Participants will have an electroencephalogram (EEG), an electrocardiogram (ECG), and an electrodermal test. Evoked potentials and magnetic resonance imaging (MRI) scans of the brain may also be taken.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 1999-08-30 |
| Est. Completion | 2010-06-02 |
What the finished NCT00001920 record still lists
NCT00001920 is an observational study that tracks outcomes without assigning an intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00001920 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00001920 about?
NCT00001920 is a clinical study titled "Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia". The purpose of this study is to explore how the brain works during particular memory tasks in people with schizophrenia and healthy volunteers. Research has shown that patients with schizophrenia have structural and functional abnormalities in the hippocampus and cerebellum of their brains. These a...
What is the current status of trial NCT00001920?
This trial is currently completed. The enrollment target is 112 participants. The study started on 1999-08-30. Estimated completion is 2010-06-02.
Who is sponsoring clinical trial NCT00001920?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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