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NCT00001771 · ClinicalTrials.gov registry record

I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers

A clinical trial, sponsored by National Institute of Mental Health (NIMH).

Completed
Registry status
112
Enrollment target

NCT00001771 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 112 participants.

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The verdict

NCT00001771 has completed, sponsored by National Institute of Mental Health (NIMH).

COMPLETED
Registry status
112 participants
Enrollment target

Study Summary

Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse. \[I-123\] Beta-CIT is a recently developed radioligand for SPECT imaging of dopamine and serotonin transporters. \[I-123\]Beta-CIT SPECT has been used at the SPECT-lab of the Clinical Brain Disorders Branch in over fifty subjects without adverse events. Due to the trace concentrations used, a pharmacological effect of Beta-CIT is unlikely and has not been observed. The purpose of this study is to use Beta-CIT and SPECT to study the expression of dopamine and serotonin transporters in vivo in normal controls and various patient populations to address hypothesized abnormalities of the transporters in different disorders and to understand the effects of genetic variations in the genes of these transporters on their in vivo expression.

Trial Details

FieldValue
Enrollment Target 112 participants
Start Date 1998-05
Est. Completion 2003-05

What the Registry Record Tells You About NCT00001771

The ClinicalTrials.gov registry entry for NCT00001771 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 112 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00001771 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001771 about?

NCT00001771 is a clinical study titled "I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers". Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse. \[I-123\] Beta-CIT is a recently developed radioligand for SPECT imaging of dopamine and serotonin transporters. \[I-123\]Beta-CIT SPECT has been used at the SPECT-...

What is the current status of trial NCT00001771?

This trial is currently completed. The enrollment target is 112 participants. The study started on 1998-05. Estimated completion is 2003-05.

Who is sponsoring clinical trial NCT00001771?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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