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NCT00001771 · ClinicalTrials.gov registry record
I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 112
- Enrollment target
NCT00001771: Completed study, sponsored by National Institute of Mental Health (NIMH).
NCT00001771 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 112 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001771 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 112 participants
- Enrollment target
Study Summary
Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse. \[I-123\] Beta-CIT is a recently developed radioligand for SPECT imaging of dopamine and serotonin transporters. \[I-123\]Beta-CIT SPECT has been used at the SPECT-lab of the Clinical Brain Disorders Branch in over fifty subjects without adverse events. Due to the trace concentrations used, a pharmacological effect of Beta-CIT is unlikely and has not been observed. The purpose of this study is to use Beta-CIT and SPECT to study the expression of dopamine and serotonin transporters in vivo in normal controls and various patient populations to address hypothesized abnormalities of the transporters in different disorders and to understand the effects of genetic variations in the genes of these transporters on their in vivo expression.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 1998-05 |
| Est. Completion | 2003-05 |
What the finished NCT00001771 record still lists
NCT00001771 is an observational study that tracks outcomes without assigning an intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00001771 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00001771 about?
NCT00001771 is a clinical study titled "I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers". Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse. \[I-123\] Beta-CIT is a recently developed radioligand for SPECT imaging of dopamine and serotonin transporters. \[I-123\]Beta-CIT SPECT has been used at the SPECT-...
What is the current status of trial NCT00001771?
This trial is currently completed. The enrollment target is 112 participants. The study started on 1998-05. Estimated completion is 2003-05.
Who is sponsoring clinical trial NCT00001771?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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