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NCT00001917 · ClinicalTrials.gov registry record
Brain Imaging in Elderly People and Individuals With Alzheimer's Disease
A clinical trial of Healthy and Alzheimers Disease, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT00001917 is a study of Healthy and Alzheimers Disease that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 150 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00001917, a study of Healthy and Alzheimers Disease, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to use brain imaging technology to study the effects of aging and Alzheimer's Disease (AD) on a specific type of brain receptor. The brain is made up of cells called neurons. The neurons communicate with one another and secrete chemicals called neurotransmitters. The neurotransmitters bind to specific sites on other neurons called receptors. Acetylcholine (ACh) is a neurotransmitter that binds to ACh receptors. In both aging and AD, the number of neurons that secrete ACh decreases and the function of some ACh receptors changes. This study will use positron emission tomography (PET) scans of the brain to study the effects of age and AD on muscarinic type 2 \[M2\], a type of ACh receptor. Participants in this study will be injected with a radioactive tracer (ligand \[F-18\] FP-TZTP) which binds to \[M2\] receptors. Participants will then undergo a PET scan in order for the density and function of \[M2\] receptors to be studied.
Conditions Studied
Interventions
- DRUG O15
- DRUG [F-18] FP-TZTP
Study Locations (1)
Maryland
- National Institute of Mental Health (NIMH) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 1999-04 |
| Est. Completion | 2005-04 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001917
The ClinicalTrials.gov registry entry for NCT00001917 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (77% lower). The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which O15 is the first listed.
NCT00001917 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00001917 about?
NCT00001917 is a clinical study titled "Brain Imaging in Elderly People and Individuals With Alzheimer's Disease". The purpose of this study is to use brain imaging technology to study the effects of aging and Alzheimer's Disease (AD) on a specific type of brain receptor. The brain is made up of cells called neurons. The neurons communicate with one another and secrete chemicals called neurotransmitters. The ne...
What is the current status of trial NCT00001917?
This trial is currently completed. The enrollment target is 150 participants. The study started on 1999-04. Estimated completion is 2005-04.
What conditions does trial NCT00001917 study?
This clinical trial studies the following conditions: Healthy, Alzheimers Disease.
What interventions are being tested in trial NCT00001917?
The interventions under investigation include: O15 (DRUG), [F-18] FP-TZTP (DRUG).
Who is sponsoring clinical trial NCT00001917?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001917 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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