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NCT00026559 · ClinicalTrials.gov registry record · NA

Effects of Arousal and Stress in Anxiety

A NA study, sponsored by National Institute of Mental Health (NIMH).

Completed
Registry status
NA
Development phase
1,418
Enrollment target

NCT00026559: Completed NA study, sponsored by National Institute of Mental Health (NIMH).

NCT00026559 is a NA study that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 1,418 participants, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00026559, a NA study, has completed, sponsored by National Institute of Mental Health (NIMH).

COMPLETED
Registry status
NA
Development phase
1,418 participants
Enrollment target

Study Summary

This study has several parts. One part will examine the influence of factors such as personality and past experience on reactions to unpleasant stimuli. Others will examine the effect of personality and emotional and attentional states on learning and memory. When confronted with fearful or unpleasant events, people can develop fear of specific cues that were associated with these events as well as to the environmental context in which the events occurred via a process called classical conditioning. Classical conditioning has been used to model anxiety disorders, but the relationship between stress and anxiety and conditioned responses remains unclear. This study will examine the relationship between cued conditioning and context conditioning . This study will also explore the acquisition and retention of different types of motor, emotional, and cognitive associative processes during various tasks that range from mildly arousing to stressful.

Primary Outcome

Subjects participated in go/no go (GNG) task condition during periods of threat of shocks and periods of safety when no shock could be administered. During the GNG stimuli were presented on a monitor. In the GNG task, participants were asked to respond to frequent 'go' stimuli ('=') by pressing the '2' on the keypad of a computer keyboard and to withhold their response to infrequent 'nogo' stimuli ('O'). Stimuli were randomly distributed. A correct go hit was a response recorded during these 200

Interventions

  • DEVICE Shock Device
  • DEVICE Auditory Startle Device

Trial Details

FieldValue
Enrollment Target 1,418 participants
Start Date 2001-01-10
Est. Completion 2022-07-28
Phase NA

What the finished NCT00026559 record still lists

NCT00026559 is an interventional study that assigns participants to a tested intervention. Its 1,418 participants enrollment target places it among the larger protocols in the corpus, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target.

The record links to 0 conditions, and to 2 interventions - of which Shock Device is the first listed.

NCT00026559 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00026559 about?

NCT00026559 is a clinical study titled "Effects of Arousal and Stress in Anxiety". This study has several parts. One part will examine the influence of factors such as personality and past experience on reactions to unpleasant stimuli. Others will examine the effect of personality and emotional and attentional states on learning and memory. When confronted with fearful or unpleas...

What is the current status of trial NCT00026559?

This trial is currently completed. It is a NA study. The enrollment target is 1,418 participants. The study started on 2001-01-10. Estimated completion is 2022-07-28.

What interventions are being tested in trial NCT00026559?

The interventions under investigation include: Shock Device (DEVICE), Auditory Startle Device (DEVICE).

Who is sponsoring clinical trial NCT00026559?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00026559's enrollment target sits among peer trials

1,418 70th of 2000 higher than 1,931 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00026559, the US trial registry maintained by the National Library of Medicine. NCT00026559 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.