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NCT00364234 · ClinicalTrials.gov registry record · NA

Low Magnitude Mechanical Stimuli Effects on Bone Structure in ESRD

A NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT00364234: Completed NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

NCT00364234 is a NA study that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00364234, a NA study, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

The proposed 6 month pilot and feasibility randomized trial will evaluate LMMS as an anabolic stimulus to bone in 30 adults on maintenance hemodialysis. The intervention will consist of 20 minute daily sessions in the home standing on an active LMMS platform or a placebo device that emits an audible hum suggestive of an active device. Each device contains an electronic monitor that documents adherence. The study will examine trabecular bone volume fraction (bone volume/total volume, BV/TV %) and architecture using microMRI, and cortical volumetric BMD and dimensions using QCT at baseline and 6 months. The hypothesis is that active LMMS will results in greater mean changes in trabecular and cortical parameters in hemodialysis patients. The proposed study will test the feasibility of conducting the intervention in dialysis patients and will generate preliminary data on rates of change in trabecular and cortical parameters in the active and placebo groups.

Interventions

  • DEVICE Low magnitude mechanical stimuli

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2006-05
Est. Completion 2007-09
Phase NA

What the finished NCT00364234 record still lists

NCT00364234 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Low magnitude mechanical stimuli is the first listed.

NCT00364234 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00364234 about?

NCT00364234 is a clinical study titled "Low Magnitude Mechanical Stimuli Effects on Bone Structure in ESRD". The proposed 6 month pilot and feasibility randomized trial will evaluate LMMS as an anabolic stimulus to bone in 30 adults on maintenance hemodialysis. The intervention will consist of 20 minute daily sessions in the home standing on an active LMMS platform or a placebo device that emits an audible...

What is the current status of trial NCT00364234?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2006-05. Estimated completion is 2007-09.

What interventions are being tested in trial NCT00364234?

The interventions under investigation include: Low magnitude mechanical stimuli (DEVICE).

Who is sponsoring clinical trial NCT00364234?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00364234's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00364234, the US trial registry maintained by the National Library of Medicine. NCT00364234 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.