National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

490 total trials 50 currently recruiting 398 completed

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.

Trial Pipeline

490 total, page 4 of 10

COMPLETED

Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT

NCT00958815

COMPLETED Phase 2

Reduced Carbohydrate Versus Fat in Obese Subjects

NCT00846040

COMPLETED Phase 2

Effects of Recombinant Human Glutamic Acid Decarboxylase on the Progression of Type 1 Diabetes in New Onset Subjects

NCT00529399

TERMINATED Phase 2

Novel Therapy to Preserve Beta Cell Function in New Onset Type 1 Diabetes

NCT00837759

COMPLETED

Long-term Follow-up of HALT-C Sustained Virological Responders

NCT00825877

COMPLETED Phase 1

Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

NCT00813228

COMPLETED Phase 3

Nortriptyline for Idiopathic Gastroparesis

NCT00765895

COMPLETED

Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3

NCT00812149

COMPLETED Phase 3

Improving Health Habits in Impoverished Populations

NCT00569595

COMPLETED Phase 2

Predicting Weight Gain and Weight Loss Associated With Overeating or Fasting

NCT00687115

COMPLETED Phase 2

Primary Prevention of Hypertension in Obese Adolescents

NCT00288158

COMPLETED

Experimental Device to Improve Colonoscopy

NCT00719641

COMPLETED Phase 2

High-Dose Ribavirin and Peginterferon to Treat Chronic Hepatitis C Genotype 1

NCT00735969

COMPLETED NA

Cognitive Behavioral Treatment of Depression in ESRD Patients on Dialysis

NCT00618475

COMPLETED

TODAY Genetics Study

NCT00722397

COMPLETED Phase 1

Viral Kinetics and Liver Gene Expression in Response to Ribavirin and Peginterferon Therapy of Chronic Hepatitis C

NCT00718172

COMPLETED Early Phase 1

Antioxidant Treatment of Type 2 Diabetes

NCT00609102

COMPLETED Phase 3

Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)

NCT00706381

COMPLETED Phase 1

Oral Nifedipine to Treat Iron Overload

NCT00712738

COMPLETED

A New Method for Determining Gastric Acid Output Using a Wireless Capsule

NCT00702533

COMPLETED NA

Physical Therapy in Women With Interstitial Cystitis

NCT00733603

COMPLETED

Effects of Diet Changes on Metabolism

NCT00523627

COMPLETED

Hepatitis C Treatment and Atherosclerosis

NCT00659256

COMPLETED NA

Parental Management of Young Children's Diabetes

NCT00847327

COMPLETED Phase 2

Intravenous CTLA4-lg Treatment in Recent Onset Type 1 Diabetes Mellitus

NCT00505375

COMPLETED NA

Computer Based Intervention for Type 2 Diabetes in Youth

NCT00570466

COMPLETED

Intraperative Assessment of Renal Perfusion Using Infrared Imaging

NCT00595179

COMPLETED Phase 2

African American Study of Kidney Disease and Hypertension ABPM Pilot Study

NCT00582777

COMPLETED NA

Addressing Emotional and Cognitive Factors in Behavioral Weight Loss Treatment

NCT00533052

COMPLETED Early Phase 1

Adolescent Self-Management of Type 1 Diabetes: an Intervention (Completed)

NCT00848705

COMPLETED NA

Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth

NCT00693511

COMPLETED Phase 3

Effect of Physical Activity on Metabolic Syndrome in Pregnancy & Fetal Outcome

NCT00647595

COMPLETED

The Stress-Hormone System in Alcohol-Dependent Subjects

NCT00536146

COMPLETED

Effects of Bariatric Surgery on Insulin

NCT00535600

COMPLETED NA

The Effect of Dietary Sitosterol on Blood Sugar and Cholesterol

NCT00531128

COMPLETED

Evaluation of Albuminuria HIV-Infected Patients

NCT00524992

TERMINATED Phase 2

Tenofovir Alone Versus Tenofovir With Emtricitabine to Treat Chronic Hepatitis B

NCT00524173

COMPLETED NA

Metabolism and Thyroid Hormone Changes During Exposure to Cold Temperatures

NCT00521729

COMPLETED

Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes Mellitus

NCT00445627

COMPLETED

Effect of Diet on Vascular Disease in Pre-Menopausal Women

NCT00484861

COMPLETED Phase 3

Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)

NCT00405704

COMPLETED Phase 2

S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis C

NCT00475176

COMPLETED Phase 1

Effects of N-acetylcysteine on Muscle Fatigue in Hemodialysis

NCT00440869

TERMINATED Phase 3

A Randomized Multicenter Double-Blind CT to Evaluate the Efficacy and Safety of Mycophenolate Mofetil . . .

NCT00451867

COMPLETED Phase 3

Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus

NCT00419562

COMPLETED

Energy Metabolism and Nutrient Absorption in Lean and Obese Individuals

NCT00414063

COMPLETED NA

Physical Therapy Trial for Pelvic Pain

NCT00434343

COMPLETED Phase 2

Botulinum Toxin Injection for the Management of BPH

NCT00451191

COMPLETED

Magnetic Resonance Angiography to Diagnose Atherosclerotic Disease

NCT00382564

COMPLETED NA

Parent Supported Weight Reduction in Down Syndrome

NCT01256112

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Phase Distribution

PhaseTrial count
Phase 1 42
Phase 2 136
Phase 3 55
Phase 4 14

What the Pipeline for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Shows

According to the ClinicalTrials.gov registry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is linked to 490 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 398 are already marked complete, representing roughly 81% of the total.

The phase mix for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 69 late-stage studies (Phase 3 and Phase 4 combined) and 178 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is Obesity with 25 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.