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NCT00001314 · ClinicalTrials.gov registry record
Investigation of Heart Function in Patients With Heart Valve Defects
A clinical trial of Aortic Valve Insufficiency and Mitral Valve Insufficiency, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Completed
- Registry status
- 200
- Enrollment target
- 1
- Study location
NCT00001314 is a study of Aortic Valve Insufficiency and Mitral Valve Insufficiency that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 200 participants, below the 1,373-participant average among 11 other Aortic Valve Insufficiency trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00001314, a study of Aortic Valve Insufficiency and Mitral Valve Insufficiency, has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- COMPLETED
- Registry status
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
In this study researchers plan to perform a diagnostic test called transesophageal echocardiography in order to see and record the movement and function of the heart. Transesophageal echocardiography is similar to an upper gastrointestinal endoscopy. Different views of the heart are taken by a small, flexible instrument positioned in the esophagus (the tube that connects the mouth to the stomach). This allows doctors to create a clear picture of the heart through the wall of the esophagus rather than from outside the body through the muscles, fat, and bones of the chest wall. During transesophageal echocardiography pictures of the heart will be taken while patients rest and as patients receive a medication called dobutamine. Dobutamine is a medication that makes the heart beat stronger and faster, similar to what exercise does to the heart. Researchers are particularly interested in studying patients with defects in the valves of the heart, especially aortic regurgitation and mitral regurgitation. Patients with these defects in the heart valves tend to develop abnormalities in the size and function of the left ventricle. The left ventricle is one of the four chambers of the heart responsible for ejecting blood out of the heart into the circulation. Researchers believe that by identifying changes in the function of heart muscle, they may be able to predict the occurrence of muscle damage due to the diseased valves. The purpose of this study is to determine whether the function of heart muscle measured during dobutamine stress transesophageal echocardiography can predict the later development of problems in the function and size of the left ventricle.
Conditions Studied
Study Locations (1)
Maryland
- National Heart, Lung and Blood Institute (NHLBI) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 1992-05 |
| Est. Completion | 2001-03 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001314
The ClinicalTrials.gov registry entry for NCT00001314 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,373-participant average among 11 other Aortic Valve Insufficiency trials with a reported enrollment target (85% lower). The listed sponsor is National Heart, Lung, and Blood Institute (NHLBI), which has 501 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Aortic Valve Insufficiency appearing as the primary indexed condition, and to 0 interventions.
NCT00001314 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00001314 about?
NCT00001314 is a clinical study titled "Investigation of Heart Function in Patients With Heart Valve Defects". In this study researchers plan to perform a diagnostic test called transesophageal echocardiography in order to see and record the movement and function of the heart. Transesophageal echocardiography is similar to an upper gastrointestinal endoscopy. Different views of the heart are taken by a smal...
What is the current status of trial NCT00001314?
This trial is currently completed. The enrollment target is 200 participants. The study started on 1992-05. Estimated completion is 2001-03.
What conditions does trial NCT00001314 study?
This clinical trial studies the following conditions: Aortic Valve Insufficiency, Mitral Valve Insufficiency.
Who is sponsoring clinical trial NCT00001314?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001314 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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