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NCT00001464 · ClinicalTrials.gov registry record
Effect of High Levels of Oxygen and Smoking on the Lungs in Human Volunteers
A clinical trial, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Completed
- Registry status
- 77
- Enrollment target
NCT00001464: Completed study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT00001464 is a clinical trial that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 77 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001464 has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- COMPLETED
- Registry status
- 77 participants
- Enrollment target
Study Summary
Patients with lung disease experiencing difficulty breathing can be treated with oxygen therapy. This involves the delivery of "extra" oxygen by a face-mask or through small tubes placed in the nose called nasal prongs. This extra oxygen can have concentrations as high as 100% pure oxygen. The concentration of oxygen in normal air is only 21%. The high concentration of oxygen can help to provide enough oxygen for all of the organs in the body. Unfortunately, breathing 100% oxygen for long periods of time can cause changes in the lungs, which are potentially harmful. Researchers believe that by lowering the concentration of oxygen therapy to 40% patients can receive it for longer periods of time without the risk of side effects. This study is designed to evaluate the effects of oxygen therapy at 100% and 40% for 12 18 hours on the lungs of normal volunteers. Results of this study will help to determine if levels of oxygen therapy currently accepted as being "safe" may actually be damaging to the lungs.
Primary Outcome
To determine whether hyperoxia of relatively limited duration (up to l8 hrs) is associated with oxidation of proteins and nucleic acids in lung cells.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 1995-08-22 |
| Est. Completion | 2007-07-10 |
What the finished NCT00001464 record still lists
NCT00001464 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 77 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00001464 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00001464 about?
NCT00001464 is a clinical study titled "Effect of High Levels of Oxygen and Smoking on the Lungs in Human Volunteers". Patients with lung disease experiencing difficulty breathing can be treated with oxygen therapy. This involves the delivery of "extra" oxygen by a face-mask or through small tubes placed in the nose called nasal prongs. This extra oxygen can have concentrations as high as 100% pure oxygen. The conce...
What is the current status of trial NCT00001464?
This trial is currently completed. The enrollment target is 77 participants. The study started on 1995-08-22. Estimated completion is 2007-07-10.
Who is sponsoring clinical trial NCT00001464?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
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