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NCT00001204 · ClinicalTrials.gov registry record
Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers
A clinical trial of Homozygous Familial Hypercholesterolemic, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Completed
- Registry status
- 73
- Enrollment target
- 1
- Study location
NCT00001204: Completed study of Homozygous Familial Hypercholesterolemic, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT00001204 is a study of Homozygous Familial Hypercholesterolemic that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 73 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001204, a study of Homozygous Familial Hypercholesterolemic, has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- COMPLETED
- Registry status
- 73 participants
- Enrollment target
- 1
- Study location
Study Summary
Homozygous familial hypercholesterolemia is a rare inherited disease of metabolism. It occurs in less than 1 in 1 million people within the United States. Patients with the disease are typically children and young adults who develop heart disease early in life. Children less than age 5 years with this disease have suffered heart attacks and death. The normal process that removes cholesterol particles from the blood stream does not work in patients with this disease. It causes cholesterol to build-up in the arteries and leads to hardening of the arteries (atherosclerosis). The goal of this study is to detect and measure atherosclerosis in these patients before it becomes permanent and potentially life threatening. Patients with this disease can participate in this study. Researchers plan to evaluate patients with homozygous familial hypercholesterolemia using new and standard methods for detecting atherosclerosis. Researchers plan to use information gathered during this study to develop new, promising treatments such as liver transplantation and gene therapy.
Primary Outcome
Descriptive data
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 1992-01-07 |
What the finished NCT00001204 record still lists
NCT00001204 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 73 participants, a relatively small participant target.
The record links to 1 condition, with Homozygous Familial Hypercholesterolemic appearing as the primary indexed condition, and to 0 interventions.
NCT00001204 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001204 about?
NCT00001204 is a clinical study titled "Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers". Homozygous familial hypercholesterolemia is a rare inherited disease of metabolism. It occurs in less than 1 in 1 million people within the United States. Patients with the disease are typically children and young adults who develop heart disease early in life. Children less than age 5 years with th...
What is the current status of trial NCT00001204?
This trial is currently completed. The enrollment target is 73 participants. The study started on 1992-01-07.
What conditions does trial NCT00001204 study?
This clinical trial studies the following conditions: Homozygous Familial Hypercholesterolemic.
Who is sponsoring clinical trial NCT00001204?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001204 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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