Brigham and Women's Hospital

Compiled by PlainTrial · August 8, 2026

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 14 of 19

Brigham and Women's Hospital

Top-decile sponsor footprint

Open and recent trials

Inducibility and Stability of Ventricular Tachycardia Inpatients Undergoing VT Ablation Under General Anesthesia

Flexibility and Strength Training in Asthma

Tranexamic Acid and Thromboelastography During Cesarean Delivery

Influence of Lumbar Ultrasound on Resident Learning Curve for Lateral Labor Epidural Placement

Combined Medication for Improved Analgesia in Superficial Pain

APOL1 Gene Variants in African American Kidney Transplant Recipients

Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism

Withdrawal of Immunosuppression in Recipients of Face and Extremity Transplants

High Omega-3/Low Omega-6 Treatment Diet for Aspirin-exacerbated Respiratory Disease (AERD)

Needle-Free Injection of Lidocaine for Local Anesthesia Prior to Trigger Digit Injection

Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices

Palliative Care Population Management Project for Integrated Care Management Program for High-Risk Patients

Salt and TH-17 in Healthy Human Subjects

The Study of Physical Activity Rewards After Knee Surgery

Personalized Risk Estimator for Rheumatoid Arthritis Family Study

Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes

Evaluating the Navajo Community Outreach and Patient Empowerment (COPE) Program

Ninvasive Cardiac Output Measurements During Cesarean Delivery Under Spinal Anesthesia.

Study of the Physical Activity in Anesthesiologists

Does 3D Laparoscopy Improve Vaginal Cuff Suture Time?

Synchronization to Improve Non-Adherence to Cardiovascular Medications

Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation

Multi-scale Modeling of Sleep Behaviors in Social Networks

Evaluation of Yoga for Substance Use Risk Factors in a School Setting

The Health Log: A Randomized Clinical Trial

Hypoglycemia and Autonomic Nervous System Function-B

Multi-center Clinical Trial of Limiting Resident Work Hours on ICU Patient Safety

Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease

A Safety, Tolerability and Efficacy Study of V158866 in Central Neuropathic Pain Following Spinal Cord Injury

Walnut Consumption, Endothelial Function, and Biomarkers

Relative Patient Benefits of a Hospital-PCMH Collaboration Within an ACO to Improve Care Transitions

Doxycycline and TUDCA in Patients With Transthyretin Amyloid Cardiomyopathy

Preoperative Cognitive Screening of Elderly Surgical Patients

Effects of Light on Melatonin and Contractions in Pregnant Women

Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions

Effects of Ranolazine on Coronary Flow Reserve in Symptomatic Diabetic Patients and CAD

Cardiovascular Inflammation Reduction Trial

Imaging Cardiac Amyloidosis: A Pilot Study Using F-18 Florbetapir Positron Emission Tomography

Impact of Community Health Workers on Adherence to Therapy for Non-Communicable Chronic Disease in Chiapas, Mexico

Role of the Isomerase Pin-1 in the Development and Treatment of Asthma

The Effects of Trazodone on Sleep Apnea Severity

Promoting Respect and Ongoing Safety Through Patient-centeredness, Engagement, Communication and Technology

Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis

Health Information Technology (HIT) Enhanced Family History Documentation and Management in Primary Care

Endoscopic Suturing for Primary Obesity Treatment

Borage and Echium Seed Oils for Asthma

Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury

Beliefs and Practice Intentions of Future Ob/Gyn Residents Regarding Reproductive Healthcare

Riluzole Augmentation Pilot in Depression (RAPID) Trial

Functional Applications of Hyperpolarized 129Xe MRI

Phase Distribution

Therapeutic Areas

What is open in the Brigham and Women's Hospital pipeline

Brigham and Women's Hospital: open-pipeline peers nationwide

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

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