Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 13 of 19

COMPLETED NA

Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery

NCT02732964

COMPLETED Phase 2

Belatacept Conversion in Proteinuric Kidney Transplant Recipients

NCT02327403

COMPLETED NA

Comparing Methods to Biopsy Pancreas Mass

NCT01663493

COMPLETED NA

Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment

NCT02538419

COMPLETED NA

Music During Labor Epidural Placement and Patient Satisfaction

NCT02734056

COMPLETED NA

Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia

NCT02147626

COMPLETED

Imputation of PaO2 From SaO2

NCT02598492

TERMINATED NA

Intrathecal Hydromorphone for Labor Analgesia

NCT02277782

COMPLETED Phase 4

Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV)

NCT02369211

TERMINATED Phase 4

The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study

NCT02253394

COMPLETED Phase 3

Strategies to Reduce Injuries and Develop Confidence in Elders

NCT02475850

COMPLETED NA

Motivational Interviewing to Enhance Adherence of Patients With Psychogenic Non-epileptic Seizures

NCT02598076

COMPLETED NA

Tele-Pharmacy Intervention to Improve Treatment Adherence

NCT02512276

TERMINATED

Improving Surgical Safety of Seniors Through Preoperative Cognitive Screening

NCT02570438

COMPLETED NA

Characterizing Upper Airway Collapse to Guide Patient Selection for Oral Appliance Therapy for Obstructive Sleep Apnea

NCT02489591

COMPLETED Phase 4

COcoa Supplement and Multivitamin Outcomes Study

NCT02422745

COMPLETED NA

Comparison of Ultrasound Guided Peripheral IV Placement With and Without Use of a Guidewire

NCT02422472

COMPLETED NA

Genomic Sequencing for Childhood Risk and Newborn Illness

NCT02422511

COMPLETED NA

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered

NCT02969343

COMPLETED Phase 2

Effect of Desipramine on Upper Airway Collapsibility and Genioglossus Muscle Activity in Patients With Obstructive Sleep Apnea - Study B

NCT02436031

COMPLETED NA

Stress and the Nervous System

NCT02339506

COMPLETED Phase 1

Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)

NCT02425579

TERMINATED Phase 3

Effects of Eicosapentaenoic Acid on Endothelial Function in Diabetic Subjects

NCT02422446

COMPLETED

Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear

NCT03312933

COMPLETED NA

Development of Countermeasures Against Adverse Metabolic Effects of Shift Work

NCT02291952

COMPLETED Phase 2

Effect of Desipramine on Genioglossus Muscle Activity in Healthy Adults Study A

NCT02428478

COMPLETED Phase 2

Tiagabine to Enhance Slow Wave Sleep in Patients With Sleep Apnea

NCT02387710

COMPLETED NA

Improving Sleep for Healthy Hearts

NCT02848859

COMPLETED

Assessment of Ventilation Using Respiratory Volume Monitor Compared to Capnography During Intravenous Sedation

NCT02860143

COMPLETED NA

Using Emergency Manuals During Interprofessional Crisis Management: Are There Unintended Consequences?

NCT03006549

COMPLETED

Effects of Clobazam on Sleep and Daytime Function in Patients With Epilepsy

NCT02911025

COMPLETED Phase 2

Tau Imaging of Chronic Traumatic Encephalopathy

NCT02191267

COMPLETED

Improving Teamwork in an Academic, Tertiary Care Labor and Delivery Unit

NCT02368535

TERMINATED

Myocardial Perfusion Echocardiography to Detect Human Heart Transplant Rejection

NCT02300870

COMPLETED NA

Neuroimaging Effects of Cognitive Behavioral Therapy in Fibromyalgia

NCT01345344

TERMINATED Phase 4

Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study

NCT01943565

COMPLETED NA

Effect of Dietary Habits on Metabolic Health

NCT02298790

COMPLETED Phase 4

Targeting Cognition in Bipolar Disorder With Pramipexole

NCT02397837

COMPLETED

Prediction of Persistent Post-Mastectomy Pain

NCT02329574

TERMINATED NA

Trial of Feedback on Blood Use

NCT02232568

COMPLETED NA

Focused Palliative Care Intervention in Advanced Heart Failure

NCT02805712

COMPLETED NA

Mail Outreach To Increase Vaccination Acceptance Through Engagement

NCT02243774

COMPLETED NA

Atrial Fibrillation, Cardiac Symptoms, and Anxiety

NCT02133365

COMPLETED

Preoperative Cognitive Screening of Surgical Patients 65 Years of Age or Older

NCT02570451

TERMINATED Early Phase 1

Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

NCT02216513

COMPLETED

Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?

NCT02339389

COMPLETED Phase 3

Intervention With Vitamin D and Omega-3 Supplements and Incident Heart Failure

NCT02271230

COMPLETED NA

Recent GDM Lifestyle Intervention

NCT01910805

COMPLETED NA

Trial of Dialysate Sodium in Chronic Hospitalized Hemodialysis Patients

NCT02145260

COMPLETED Phase 4

Safety and Efficacy of Saxagliptin for Glycemic Control in Non-Critically Ill Hospitalized Patient

NCT02182895

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.