Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 15 of 19

TERMINATED NA

Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse

NCT01594372

COMPLETED NA

Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B

NCT01738009

COMPLETED NA

Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study A

NCT01728974

COMPLETED Phase 3

Intraoperative Trocar Slippage Study

NCT01476748

TERMINATED

PET/CT to Predict Response to Infliximab Therapy in Patients With Crohn's Disease

NCT01759017

TERMINATED NA

Medical Use of Song In Critical Care (MUSIC)

NCT01763736

COMPLETED NA

Estimating Apnea Phenotypes From Polysomnography: Oxygen

NCT01751971

COMPLETED NA

The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study

NCT01691781

TERMINATED NA

Assessment of Sleep Apnea and Its Causes Before and After Weight Loss Surgery

NCT01712269

COMPLETED NA

The VALIDATE-D Study

NCT01635062

COMPLETED Phase 1

Safety Study of Sirolimus and Hydroxychloroquine in Women With Lymphangioleiomyomatosis

NCT01687179

COMPLETED NA

Fatigue Countermeasure Program in Operational Flight Controllers

NCT01744678

COMPLETED NA

Fire Fighter Fatigue Management Program: Operation Fight Fatigue

NCT01672502

COMPLETED NA

Evaluation of a Pocket-Sized Ultrasound Device As an Aid to the Physical Examination

NCT01948076

COMPLETED NA

VITamin D and OmegA-3 TriaL: Effects on Bone Structure and Architecture (VITAL)

NCT01747447

COMPLETED NA

Combination Therapy to Treat Sleep Apnea

NCT01633827

COMPLETED NA

Investigating the Effects of Evening Light Exposure on Melatonin Suppression, Alertness and Nocturnal Sleep

NCT01586039

COMPLETED NA

Evaluation of Yoga for Sleep Disturbances in Post Traumatic Stress Disorder (PTSD)

NCT01556074

COMPLETED Phase 1

A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus

NCT01421355

COMPLETED Phase 2

Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic Hypotension

NCT01520207

COMPLETED NA

Thoracic Blocks Versus Thoracic Epidural and Patient Controlled Anesthesia in Traumatic Rib Fracture Patients

NCT01599403

COMPLETED NA

Sleep Duration Required to Restore Performance During Chronic Sleep Restriction

NCT01581125

COMPLETED

A National Study of Intravenous Medication Errors

NCT02359734

COMPLETED Phase 2

L-Arginine, Vascular Response and Mechanisms

NCT01482247

COMPLETED

Observational Cohort Study of Chronic Low Back Pain

NCT01355237

COMPLETED NA

Non-drug Interventions for Migraines

NCT01545466

COMPLETED NA

Comprehensive Intervention to Evaluate Outcomes AND Cost in Hospitalized Surgical Patients With Diabetes Mellitus (DM)

NCT02065050

TERMINATED NA

The Impact of Nebivolol Versus Metoprolol on Quality of Life

NCT01441570

COMPLETED

Role of Stress CMR in Predicting Adverse Clinical Events in Patients With Known or Suspected IHD

NCT01821924

COMPLETED NA

Brain Mechanisms of Acupuncture Treatment in Chronic Low Back Pain

NCT01595451

COMPLETED NA

Brain Imaging Study of Acupuncture in Chronic Low Back Pain

NCT01614639

COMPLETED NA

Back Pain Response to Different Acupuncture Methods

NCT01598974

COMPLETED

Identifying Biomarkers That Distinguish PTSD and mTBI Using Advanced Magnetic Resonance Spectroscopy

NCT02927288

TERMINATED Phase 4

Changes in Cardiac Function in COPD Patients After Administration of Budesonide/Formoterol (Symbicort®) Versus Placebo

NCT01760304

COMPLETED Phase 2

Atazanavir and Endothelial Function in Older HIV Patients

NCT03019783

COMPLETED NA

Intensive Discharge Intervention in Diabetes

NCT02122926

COMPLETED NA

Use of Electronic Health Records for Addressing Overweight and Obesity in Primary Care

NCT01480466

COMPLETED NA

A Pilot Project Exploring the Impact of Whole Genome Sequencing in Healthcare

NCT01736566

COMPLETED Phase 3

Study of Vitamin D and Omega-3 Supplementation for Preventing Diabetes

NCT01633177

COMPLETED NA

Tobacco Treatment Outreach to Reduce Disparities for Primary Care Populations

NCT01156610

COMPLETED NA

Application Time of Plaster-of-Paris Splint Packs Compared to Bulk Supplies Following Standard Orthopaedic Procedure

NCT01602484

COMPLETED NA

A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline

NCT01669915

COMPLETED Phase 3

Add on Lacosamide Versus High Dose Monotherapy

NCT01345058

COMPLETED NA

Memory Consolidation in Obstructive Sleep Apnea

NCT01800786

COMPLETED Phase 4

Teriparatide for Joint Erosions in Rheumatoid Arthritis: The TERA Trial

NCT01400516

COMPLETED NA

Adding Value in Knee Arthroplasty Post-total Knee Replacement (TKR) Care Navigator Trial

NCT01540851

COMPLETED Phase 2

Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis

NCT01214187

COMPLETED Phase 4

Vasopressin Administration During Laparoscopic Myomectomy: a Randomized Controlled Trial

NCT01393704

COMPLETED Phase 3

Improving Management of Outpatient Actionable Test Results

NCT01385982

TERMINATED NA

The Effect(s) of Sevelamer Carbonate (Renvela) on Atherosclerotic Plaque Inflammation Judged by FDG-PET Scan

NCT01238588

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.