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NCT01817907 · ClinicalTrials.gov registry record · NA
The Effects of Trazodone on Sleep Apnea Severity
A NA study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT01817907: Completed NA study, sponsored by Brigham and Women's Hospital.
NCT01817907 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01817907, a NA study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
In Obstructive sleep apnea (OSA), the upper airway closes over and over again during sleep. This leads to disrupted sleep (waking up during the night), daytime sleepiness, and an increased risk for developing high blood pressure. Currently, the best treatment for obstructive sleep apnea is sleeping with a mask that continuously blows air into the nose (i.e. Continuous positive airway pressure \[CPAP\] treatment). While CPAP treatment stops the upper airway from closing in most people, many people have difficulty sleeping with the mask in place and therefore do not use the CPAP treatment. This research study is being conducted to learn whether using a sedative will improve OSA severity by altering some of the traits that are responsible for the disorder.
Primary Outcome
The Apnea-Hypopnea Index (AHI) is an index of sleep apnea severity that encompasses the frequency of apneas (cessations in breathing) and hypopneas (reductions in airflow).
Interventions
- DRUG Trazodone
- DRUG Placebo pill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2013-03 |
| Est. Completion | 2014-12 |
| Phase | NA |
What the finished NCT01817907 record still lists
NCT01817907 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Trazodone is the first listed.
NCT01817907 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01817907 about?
NCT01817907 is a clinical study titled "The Effects of Trazodone on Sleep Apnea Severity". In Obstructive sleep apnea (OSA), the upper airway closes over and over again during sleep. This leads to disrupted sleep (waking up during the night), daytime sleepiness, and an increased risk for developing high blood pressure. Currently, the best treatment for obstructive sleep apnea is sleeping ...
What is the current status of trial NCT01817907?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2013-03. Estimated completion is 2014-12.
What interventions are being tested in trial NCT01817907?
The interventions under investigation include: Trazodone (DRUG), Placebo pill (DRUG).
Who is sponsoring clinical trial NCT01817907?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01817907's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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