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NCT01691612 · ClinicalTrials.gov registry record · Phase 2

Role of the Isomerase Pin-1 in the Development and Treatment of Asthma

A Phase 2 study, sponsored by Brigham and Women's Hospital.

Completed
Registry status
Phase 2
Development phase
14
Enrollment target

NCT01691612 is a Phase 2 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 14 participants.

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The verdict

NCT01691612, a Phase 2 study, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
Phase 2
Development phase
14 participants
Enrollment target

Study Summary

Pin1 is activated in asthmatic airways, increasing cytokine mRNA stability and eosinophil survival. This study is designed to test whether the Pin1 enzyme regulates TLR/IL-1R signal pathways in multiple cells in asthma.

Interventions

  • BIOLOGICAL installation of D. pteronyssinus allergens

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2013-03
Est. Completion 2015-05
Phase Phase 2

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT01691612

The ClinicalTrials.gov registry entry for NCT01691612 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which installation of D. pteronyssinus allergens is the first listed.

NCT01691612 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01691612 about?

NCT01691612 is a clinical study titled "Role of the Isomerase Pin-1 in the Development and Treatment of Asthma". Pin1 is activated in asthmatic airways, increasing cytokine mRNA stability and eosinophil survival. This study is designed to test whether the Pin1 enzyme regulates TLR/IL-1R signal pathways in multiple cells in asthma.

What is the current status of trial NCT01691612?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2013-03. Estimated completion is 2015-05.

What interventions are being tested in trial NCT01691612?

The interventions under investigation include: installation of D. pteronyssinus allergens (BIOLOGICAL).

Who is sponsoring clinical trial NCT01691612?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.