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NCT02194088 · ClinicalTrials.gov registry record · Phase 3
Combined Medication for Improved Analgesia in Superficial Pain
A Phase 3 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Phase 3
- Development phase
- 100
- Enrollment target
NCT02194088: Completed Phase 3 study, sponsored by Brigham and Women's Hospital.
NCT02194088 is a Phase 3 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 100 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02194088, a Phase 3 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 100 participants
- Enrollment target
Study Summary
This research study is being done to assess if a combination of medications can enhance the relief of superficial pain (pain at the surface of the skin, such as sunburn pain). The investigators also want to find out if certain genes may be linked to individual differences in experienced efficacy of pain killers. The combination of medications under investigation is diclofenac and atropine. Diclofenac has been approved by the U.S. Food and Drug Administration (FDA) to treat pain. Atropine has been approved by the FDA to treat certain types of poisoning, heartbeat problems, and other diseases but atropine is not approved to treat pain. However, atropine has been used for many years in different European countries to treat painful conditions such as stomach cramps.This research study will compare diclofenac and atropine to placebo.
Primary Outcome
Pain scores on standardized experimental pain testing, with collection of Visual analog scales (VAS) on a 0-100 scale 0 (no pain)- 100 (worst pain imaginable) Higher values represent a worse outcome (more pain)
Interventions
- DRUG Placebo
- DRUG Diclofenac and Atropine combination drug
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2014-04 |
| Est. Completion | 2017-06 |
| Phase | Phase 3 |
What the finished NCT02194088 record still lists
NCT02194088 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02194088 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02194088 about?
NCT02194088 is a clinical study titled "Combined Medication for Improved Analgesia in Superficial Pain". This research study is being done to assess if a combination of medications can enhance the relief of superficial pain (pain at the surface of the skin, such as sunburn pain). The investigators also want to find out if certain genes may be linked to individual differences in experienced efficacy of ...
What is the current status of trial NCT02194088?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 100 participants. The study started on 2014-04. Estimated completion is 2017-06.
What interventions are being tested in trial NCT02194088?
The interventions under investigation include: Placebo (DRUG), Diclofenac and Atropine combination drug (DRUG).
Who is sponsoring clinical trial NCT02194088?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02194088's enrollment target sits among peer trials
100 1681st of 2000 higher than 288 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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