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NCT00432536 · ClinicalTrials.gov registry record
Redesigning Cardiac Surgery to Reduce Neurologic Injury
A clinical trial of Cardiovascular Disease and Surgery, sponsored by Dartmouth-Hitchcock Medical Center.
- Completed
- Registry status
- 469
- Enrollment target
- 3
- Study locations
NCT00432536 is a study of Cardiovascular Disease and Surgery that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 469 participants, below the 2,710-participant average among 136 other Cardiovascular Disease trials with a reported enrollment target (83% lower). The trial reports 3 study locations across 2 states.
The verdict
NCT00432536, a study of Cardiovascular Disease and Surgery, has completed, sponsored by Dartmouth-Hitchcock Medical Center.
- COMPLETED
- Registry status
- 469 participants
- Enrollment target
- 3
- Study locations
Study Summary
Neurologic injuries are frequent and devastating complications following cardiac surgery. Previous work conducted by our research group and others has identified the principal mechanisms creating both overt and subtle neurologic injuries after cardiac surgery. Current work by our group has identified that the causes (thrombotic/lipid emboli, cerebral hypoperfusion \& hypotension, and gaseous emboli) of these injuries are byproducts of processes of surgical and perfusion care. This insight suggests that the redesign of clinical strategies and techniques to prevent the occurrence of these intraoperative sources of damage may provide an opportunity to reduce the risk of neurologic injury after cardiac surgery. The goal of this research is to identify modifiable clinical strategies and techniques of surgical and perfusion care associated with the causes (thrombotic/lipid emboli, cerebral hypoperfusion \& hypotension, and gaseous emboli) of neurologic injury secondary to coronary artery bypass graft (CABG) surgery, and subsequently to redesign these processes to reduce a patient's risk of a neurologic injury.
Conditions Studied
Interventions
- OTHER Quality improvement intervention
Study Locations (3)
New Hampshire
- Dartmouth-Hitchcock Medical Center - Lebanon
- Catholic Medical Center - Manchester
Maine
- Maine Medical Center - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 469 participants |
| Start Date | 2002-10 |
| Est. Completion | 2012-02 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00432536
The ClinicalTrials.gov registry entry for NCT00432536 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 469 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,710-participant average among 136 other Cardiovascular Disease trials with a reported enrollment target (83% lower). The listed sponsor is Dartmouth-Hitchcock Medical Center, which has 427 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Cardiovascular Disease appearing as the primary indexed condition, and to 1 intervention - of which Quality improvement intervention is the first listed.
NCT00432536 reports 3 study locations spanning 2 distinct geographic areas - top geographies include New Hampshire, Maine.
Frequently Asked Questions
What is clinical trial NCT00432536 about?
NCT00432536 is a clinical study titled "Redesigning Cardiac Surgery to Reduce Neurologic Injury". Neurologic injuries are frequent and devastating complications following cardiac surgery. Previous work conducted by our research group and others has identified the principal mechanisms creating both overt and subtle neurologic injuries after cardiac surgery. Current work by our group has identifie...
What is the current status of trial NCT00432536?
This trial is currently completed. The enrollment target is 469 participants. The study started on 2002-10. Estimated completion is 2012-02.
What conditions does trial NCT00432536 study?
This clinical trial studies the following conditions: Cardiovascular Disease, Surgery.
What interventions are being tested in trial NCT00432536?
The interventions under investigation include: Quality improvement intervention (OTHER).
Who is sponsoring clinical trial NCT00432536?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00432536 being conducted?
This trial has 3 study locations across Maine, New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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