Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05495841 · ClinicalTrials.gov registry record

OPTiMASK: Comparison of Pre-oxygenation With Standard Face Mask Combined With High Flow Nasal Oxygen With Pre-oxygenation With Standard Face Mask Alone

A clinical trial of Surgery, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
80
Enrollment target
1
Study location

NCT05495841: Completed study of Surgery, sponsored by Beth Israel Deaconess Medical Center.

NCT05495841 is a study of Surgery that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 80 participants, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05495841, a study of Surgery, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
80 participants
Enrollment target
1
Study location

Study Summary

This is an observational, prospective study of patients undergoing a surgical procedure. Three parallel studies are taking place with collaborators in other countries. This study aims to bring novel insights regarding the benefits of pre-oxygenation combining standard oxygen facemask with high-flow nasal oxygen (HFNO), as opposed to standard oxygen facemask alone by assessing end-tidal oxygen (ETO2) levels after intubation.

Primary Outcome

Lowest EtO2 value within the two minutes following tracheal intubation

Conditions Studied

Interventions

  • DEVICE Pre-oxygenation

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2022-08-18
Est. Completion 2023-06-30

What the finished NCT05495841 record still lists

NCT05495841 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Surgery appearing as the primary indexed condition, and to 1 intervention - of which Pre-oxygenation is the first listed.

NCT05495841 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05495841 about?

NCT05495841 is a clinical study titled "OPTiMASK: Comparison of Pre-oxygenation With Standard Face Mask Combined With High Flow Nasal Oxygen With Pre-oxygenation With Standard Face Mask Alone". This is an observational, prospective study of patients undergoing a surgical procedure. Three parallel studies are taking place with collaborators in other countries. This study aims to bring novel insights regarding the benefits of pre-oxygenation combining standard oxygen facemask with high-flow ...

What is the current status of trial NCT05495841?

This trial is currently completed. The enrollment target is 80 participants. The study started on 2022-08-18. Estimated completion is 2023-06-30.

What conditions does trial NCT05495841 study?

This clinical trial studies the following conditions: Surgery.

What interventions are being tested in trial NCT05495841?

The interventions under investigation include: Pre-oxygenation (DEVICE).

Who is sponsoring clinical trial NCT05495841?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05495841 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Surgery

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05495841's enrollment target sits among peer trials

80 67th of 120 higher than 49 of 120 other Surgery trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Surgery trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01243931 · 80 participants · NA

    Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

  • NCT01659203 · 80 participants · Phase 1

    Proton or Photon RT for Retroperitoneal Sarcomas

  • NCT01803451 · 80 participants · Early Phase 1

    Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

  • NCT01964859 · 80 participants · Phase 2

    Feasibility Study for Fibroblast Autologous Skin Grafts

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05495841, the US trial registry maintained by the National Library of Medicine. NCT05495841 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.